A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), working in partnership with researchers at Mount Sinai Hospital in New York, has discovered a new molecular mechanism mediated by nuclear receptors ...
Apr 3, 2020
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168
An industrial chemical—phased out since 2002, but previously used in stain and water-repellent products and firefighting foam—alters the gut microbiome of mice and could have implications for human health, according to ...
Jan 22, 2020
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134
A study led by scientists at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Communications proposes chaperone protein Hps70 as an attractive therapeutic target for the treatment of Kennedy's ...
Aug 8, 2019
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15
USC scientists report that a novel time-keeping mechanism within liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted.
Dec 11, 2018
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955
Two University of Houston scientists are reporting that defects in a portion of the brain's hippocampus, called the dentate gyrus, is regulated by the nuclear receptor LXRβ (Liver X receptor Beta). The dentate gyrus, or ...
Mar 14, 2018
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1016
The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained ...
May 16, 2017
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21
In real estate, location is key. It now seems the same concept holds true when it comes to stopping pain.
Feb 3, 2016
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167
Imagine if you could carry a credit card-size record of all the 3 billion A's, T's C's, and G's that make up the alphabet soup of your genome. A simple swipe of the card could inform your physician right away if a drug being ...
Jul 12, 2015
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192
Preventing weight gain, obesity, and ultimately diabetes could be as simple as keeping a nuclear receptor from being activated in a small part of the brain, according to a new study by Yale School of Medicine researchers.
Aug 1, 2014
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1
Researchers at Sanford-Burnham Medical Research Institute have determined the complete three-dimensional structure of a protein called HNF-4α. HNF-4α controls gene expression in the liver and pancreas, switching genes on ...
Mar 13, 2013
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