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Three new genetic links to colorectal cancer

Vanderbilt-Ingram Cancer Center investigators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new in ...

Cancer created Dec 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Single change in genetic sequence can significantly impact BMI variability

(Medical Xpress)—One small change to the DNA sequence can cause more weighty changes to the human body, according to a new study released today.

Genetics created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast

First evidence for genetic cause for Barrett's oesophagus found

Genetic variations that are linked with the onset of Barrett's oesophagus (BE), a pre-cancerous condition of the lower end of the gullet, have been identified for the first time. The discovery of variations in regions on ...

Genetics created Sep 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

New study discovers genomic variant that increases risk of some brain tumors

People who carry a "G" instead of an "A" at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the ...

Genetics created Aug 26, 2012 | popularity not rated yet | comments 0 | with audio podcast

Three new genetic links to breast cancer identified

(Medical Xpress) -- An international team of researchers has identified three new genetic loci associated with an increased susceptibility to breast cancer. As described in their paper published in Nature Ge ...

Genetics created Jan 23, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast report

With two new methods, scientists hope to improve genome-wide association studies

As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...

Genetics created Apr 26, 2013 | popularity not rated yet | comments 0 | with audio podcast

Genetic discovery found to influence obesity in people of African ancestry

The largest genetic search for "obesity genes" in people of African ancestry has led to the discovery of three new regions of the human genome that influence obesity in these populations and others.

Genetics created Apr 15, 2013 | popularity not rated yet | comments 0 | with audio podcast

Shutting down DNA construction: How senescence halts growth of potential cancers

Researchers from The Wistar Institute explain a new molecular mechanism behind the phenomenon of oncogene-induced senescence. By depriving the cell of the ability to make new nucleotides—the building blocks ...

Cancer created Apr 04, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Largest study reveals five major psychiatric disorders share common genetic risk factors

For the first time, scientists have discovered that five major psychiatric disorders—autism, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder and schizophrenia—share several common ...

Psychology & Psychiatry created Feb 27, 2013 | popularity 5 / 5 (1) | comments 0

Genetic variation doubles risk of aortic valve calcification

Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic ...

Cardiology created Feb 06, 2013 | popularity not rated yet | comments 0 | with audio podcast

More links found between schizophrenia, cardiovascular disease

A new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular diseas ...

Genetics created Jan 31, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Search for epigenetic decoder leads scientists to Rett Syndrome

(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...

Medical research created Dec 21, 2012 | popularity 5 / 5 (1) | comments 5 | with audio podcast

The mu opioid receptor genotype may be a marker for those who drink for alcohol's rewarding effects

Previous research had identified an individual's subjective response to alcohol as a marker of alcoholism risk. The A118G single nucleotide polymorphism (SNP) of the mu opioid receptor (OPRM1) gene had also been previously ...

Addiction created Dec 14, 2012 | popularity not rated yet | comments 0 | with audio podcast

Carriers of gene variant appear less likely to develop heart disease

Scientists at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University have discovered a new gene mechanism that appears to regulate triglyceride levels. This pathway may protect carriers of ...

Genetics created Dec 14, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New method helps link genomic variation to protein production

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according ...

Genetics created Nov 06, 2012 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Nucleotide

Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. Additionally, nucleotides play central roles in metabolism. In that capacity, they serve as sources of chemical energy (adenosine triphosphate and guanosine triphosphate), participate in cellular signaling (cyclic guanosine monophosphate and cyclic adenosine monophosphate), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, flavin adenine dinucleotide, flavin mononucleotide, and nicotinamide adenine dinucleotide phosphate).

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