Genetics

Researchers extend human epigenomic map

Ten years ago, scientists announced the end of the Human Genome Project, the international attempt to learn which combination of four nucleotides—adenine, thymine, cytosine, and guanine—is unique to homo sapien DNA. This ...

Diseases, Conditions, Syndromes

Quadratic leap in detecting smallest unit of genetic change

Scientists at Rice University and the University of Washington (UW) this week unveiled a groundbreaking new method for detecting minute changes known as single nucleotide polymorphisms (SNPs) in the human genome. The human ...

Oncology & Cancer

Three new genetic links to colorectal cancer

Vanderbilt-Ingram Cancer Center investigators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new insight ...

Medical research

Search for epigenetic decoder leads scientists to Rett Syndrome

(Medical Xpress)—A few years ago, scientists discovered an unexpected layer of information woven into the genetic code – a nucleotide called 5-hydroxymethylcytosine, or 5hmC. Its meaning was unknown at the time, but a ...

Genetics

New method helps link genomic variation to protein production

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according ...

Oncology & Cancer

Scientists discover gene switch important in cancer

Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published ...

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