A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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When a patient has diabetes, doctors typically prescribe insulin, along with diet and exercise. When a patient has high blood pressure, we prescribe medication, and we also reinforce the importance of healthy eating, exercise, ...
Feb 6, 2018
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Researchers at the University of Granada led a novel study in mice that shows that sigma‑1 receptor blockers cause white blood cells or leukocytes to relieve pain when a tissue is inflamed
Feb 5, 2018
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For the first time, scientists at the University of North Carolina School of Medicine and collaborators solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created ...
Jan 4, 2018
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The current opioid epidemic is destroying lives, families, and communities. Medication is widely considered to be the most effective treatment, but far too few people who could benefit are actually treated.
Dec 6, 2017
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In a new study, researchers have characterized the effects of a series of opioids on proteins in the brain other than opioid receptors. In the British Journal of Pharmacology study, several synthetic opioids inhibited serotonin ...
Dec 6, 2017
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Opioid drugs are the most widely prescribed and effective type of pain medication. But they are highly addictive and have some unpleasant and potentially deadly side effects.
Dec 5, 2017
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With opioid addiction officially declared a public health emergency in the U.S., medical intervention to treat the illness is increasingly important in responding to the epidemic. Now, a new study concludes that two of the ...
Nov 14, 2017
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A potential new antidepressant and antianxiety treatment with a unique mechanism of action has been developed by scientists at the University of Bath.
Nov 6, 2017
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Mount Sinai researchers have identified unique structural, biological and chemical insights in the way different opioid drugs activate the receptors and specific signaling pathways responsible for the drug's beneficial and ...
Sep 13, 2017
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