Bone-related diseases are the most common cause of severe long-term pain and reduced quality of life for millions of people. They include osteoporosis, periodontitis and rheumatoid arthritis – the number of people suffering ...
Oct 8, 2018
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In a new study published in November in Scientific Reports, New York University College of Dentistry (NYU Dentistry) researchers investigating the catabolic effect of parathyroid hormone (PTH) in hyperparathyroidism (HPT) ...
Dec 7, 2017
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Researchers from Hong Kong Baptist University and colleagues have demonstrated that a molecule called miR-214-3p plays a role in inhibiting bone formation. MiR-214-3p is a microRNA (miRNA): a non-coding RNA involved in regulating ...
Mar 28, 2017
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Most existing treatments for pathological bone loss inhibit osteoclasts (bone-destroying cells) to limit bone degradation. However, by doing this, they also prevent bone formation since it is stimulated by the presence of ...
Feb 12, 2015
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Osteonecrosis of the jaw is a debilitating and painful condition in which oral lesions develop in individuals taking drugs such as bisphosphonate or denosumab, which are commonly used in treatments for osteoporosis and for ...
Nov 25, 2014
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Bone homeostasis requires precise balance between deposition of new bone by osteoblasts and resorption of old bone by osteoclasts. Bone diseases, including osteoporosis and rheumatoid arthritis, are the result of increased ...
Dec 9, 2013
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The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy ...
Dec 4, 2013
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Researchers from ETH Zurich have successfully demonstrated, for the first time in vivo, how bone tissue responds to local mechanical stimuli that control bone formation. The study reveals how important it is to stimulate ...
Sep 2, 2013
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Bone integrity requires skeletal remodeling, which involves both bone formation and resorption. It has been previously shown that the formation of new bone is triggered by degradation of older bone. However, it is unknown ...
Aug 1, 2013
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(Medical Xpress)—Human bone breaks down and regenerates naturally all the time, in a perfectly balanced dance that maintains skeletal integrity.
Jun 19, 2013
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