Key find for early bladder cancer treatment
Aggressive forms of bladder cancer involve the protein PODXL – a discovery that could hold the key to improved treatment, according to researchers at Lund University, Uppsala University and KTH in Sweden.
Cancer
May 23, 2013 |
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New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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New nanoparticles that shut off cancer genes shrink tumors in mice
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...
Cancer
Aug 15, 2012 |
5 / 5 (7) |
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Thioridazine kills cancer stem cells in human while avoiding toxic side-effects of conventional cancer treatments
A team of scientists at McMaster University has discovered a drug, thioridazine, successfully kills cancer stem cells in the human while avoiding the toxic side-effects of conventional cancer treatments.
Cancer
May 24, 2012 |
4.7 / 5 (55) |
5
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Gene mutation as cause of breast and ovarian cancer
A change to the so-called TERT gene considerably increases the risk of breast and ovarian cancer. This is the result of a current, multicenter study in which the University Department of Gynaecology and the ...
Cancer
May 10, 2013 |
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Genome-scale study of 100 cell lines pinpoints vulnerabilities in ovarian cancer
Cancer is not invincible but its weaknesses can be difficult to detect. An effort known as Project Achilles — named after the Greek warrior whose one vulnerability led to his undoing — was launched to develop a ...
Cancer
Jul 11, 2011 |
5 / 5 (1) |
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Short fasting cycles work as well as chemotherapy in mice
Man may not live by bread alone, but cancer in animals appears less resilient, judging by a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.
Cancer
Feb 08, 2012 |
4.7 / 5 (17) |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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PARP inhibitors may have clinical utility in HER2-positive breast cancers
Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive ...
Cancer
Sep 17, 2012 |
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Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis
Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...
Cancer
Jan 29, 2013 |
5 / 5 (1) |
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Origin of aggressive ovarian cancer discovered
Cornell University researchers have discovered a likely origin of epithelial ovarian cancer (ovarian carcinoma), the fifth leading cause of cancer death among women in the United States.
Cancer
Mar 06, 2013 |
5 / 5 (1) |
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Team finds biological indicator of aggressive, recurrent forms of prostate cancer
(Medical Xpress)—In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness ...
Cancer
Aug 27, 2012 |
5 / 5 (1) |
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Ovarian cancer stem cell study puts targeted therapies within reach
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer ...
Cancer
Jan 07, 2013 |
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New type of drug leads to hope against resistant ovarian cancer
Scientists at USC have discovered a new type of drug for the treatment of ovarian cancer that works in a way that should not only decrease the number of doses that patients need to take, but also may make it effective for ...
Cancer
Oct 03, 2012 |
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Using millions of years of cell evolution in the fight against cancer
As the medical community continues to make positive strides in personalized cancer therapy, scientists know some dead ends are unavoidable. Drugs that target specific genes in cancerous cells are effective, but not all proteins ...
Genetics
Aug 07, 2012 |
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