Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby ...
Jun 19, 2020
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Delta opioid receptors have a built-in mechanism for pain relief and can be precisely targeted with drug-delivering nanoparticles—making them a promising target for treating chronic inflammatory pain with fewer side effects, ...
Jun 15, 2020
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Opioids regulate the feelings of pleasure and pain in the brain. A study by the national Turku PET Centre in Finland shows that age, sex and smoking influence μ-opioid receptor density in the brain. The results of the study ...
May 28, 2020
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Fast communication between our brain cells—or neurotransmission as it is called—is hugely important for our brain to work properly. Some of the messengers involved in this form of communication are neuropeptides, which ...
Mar 31, 2020
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Like buoys bobbing on the ocean, many receptors float on the surface of a cell's membrane with a part sticking above the water and another underwater, inside the cell's cytoplasm. But for cells to function, these receptors ...
Feb 6, 2020
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This is big news for Irritable Bowel Syndrome (IBS) patients: 11 percent of the world's population suffers from IBS, but the fight against chronic pain has taken a major step forward with scientists identifying receptors ...
Oct 16, 2019
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The annual cost of chronic pain in the United States is estimated to be more than $635 billion in direct medical costs, lost productivity and disability programs. One in five adults—50 million Americans—report living ...
Jul 10, 2019
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G-protein-coupled receptors are present in many neurological and psychological disorders thanks to the activation of G proteins. In addition to activating the G protein, they are also able to activate proteins responsible ...
Mar 28, 2019
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Chronic pain involves more than just hurting. People suffering from pain often experience sadness, depression and lethargy. That's one reason opioids can be so addictive—they not only dampen the pain but also make people ...
Mar 13, 2019
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A team of researchers from Université Paris-Saclay and Université Paris Descartes has developed a nano-drug that has been found to reduce pain in rodents. In their paper published in the journal Science Advances, the group ...
