Heart failure is often identified only when the heart has already deteriorated. This is in large part because the cause is unknown for about 70% of people who experience heart failure.
Feb 13, 2023
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319
Scientists at the Francis Crick Institute have uncovered how cells lining the lung airways change their metabolism, and how this process is key to helping the lungs heal after infection or damage.
Feb 13, 2023
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97
As we age, the end caps of our chromosomes, called telomeres, gradually shorten. Now, Salk scientists have discovered that when telomeres become very short, they communicate with mitochondria, the cell's powerhouses. This ...
Feb 8, 2023
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323
Metastasis, the process by which cancer cells leave the primary tumor and spread to other tissues to seed new cancerous growth, causes most cancer deaths. There is a clear need to better understand the processes that enable ...
Feb 1, 2023
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79
Researchers from the University of Michigan Rogel Cancer Center have found a mechanism for why a subset of patients' tumors grow, rather than shrink, when faced with immunotherapy.
Jan 18, 2023
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40
Neuropathic pain is a type of chronic pain caused by damage to the nervous system due mainly to metabolic diseases such as diabetes and arthritis, or the side effects of some kinds of chemotherapy. It is believed to affect ...
Jan 10, 2023
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43
Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...
Jan 5, 2023
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59
Lactate, a major product of glycolysis in mammals, is significantly increased in pathological states such as tumors, sepsis and autoimmune diseases, which is known as the Warburg effect. Despite being an important metabolic ...
Jan 4, 2023
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34
The great hope of cancer immunotherapy is to bolster our own immune cells in specific ways to keep cancer cells from evading our immune system. Although much progress has been made, immunotherapy does not always work well. ...
Dec 19, 2022
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39
Some species of gut-dwelling bacteria activate nerves in the gut to promote the desire to exercise, according to a study in mice that was led by researchers at the Perelman School of Medicine at the University of Pennsylvania. ...
Dec 14, 2022
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