Alzheimer's disease & dementia

Pathway discovered that prevents buildup of Alzheimer's protein

St. Jude Children's Research Hospital scientists have discovered a pathway that functions like a car wash to prevent the buildup of a toxic protein associated with Alzheimer's disease. The report appeared online today in ...

Oncology & Cancer

Nutritional cues regulate pancreatic tumor's 'cell drinking'

Desperate for nutrients, rapidly growing pancreatic tumors resort to scavenging "fuel" through an alternative supply route, called macropinocytosis. Scientists are hopeful that blocking this process, often described as "cellular ...

Oncology & Cancer

Drug makes tumors more susceptible to chemo

Many chemotherapy drugs kill cancer cells by severely damaging their DNA. However, some tumors can withstand this damage by relying on a DNA repair pathway that not only allows them to survive, but also introduces mutations ...

Medications

Potential drug targets for ALS and FTD identified in two studies

A pair of collaborative studies led by Fen-Biao Gao, Ph.D., have identified two potential drug targets for the diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The studies, which appear in Nature ...

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