Medications

Drug linked to lower risk of dementia in people with diabetes

People with diabetes are twice as likely to develop dementia as those without the disease. In a new study, people with newly diagnosed type 2 diabetes who took the diabetes drug pioglitazone were less likely to later develop ...

Diabetes

Pioglitazone cuts diabetes risk after ischemic stroke, TIA

(HealthDay)—For insulin-resistant patients with recent ischemic stroke or transient ischemic attack, pioglitazone is associated with reduced risk of diabetes, according to a study published online July 27 in Diabetes Care.

Neuroscience

Diabetes drug relieves nicotine withdrawal

A drug commonly used to treat Type II diabetes abolishes the characteristic signs of nicotine withdrawal in rats and mice, according to new research published in JNeurosci. The finding may offer an important new strategy ...

Alzheimer's disease & dementia

Diabetes medication reduces dementia risk

Treating people with type 2 diabetes, also known as 'age-related diabetes' with antidiabetics reduces their risk for Alzheimer's and other types of dementia. The risk is most significantly reduced by the drug pioglitazone. ...

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Pioglitazone

Pioglitazone is a prescription drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action. Pioglitazone is marketed as trademarks Actos in the USA, Canada, the UK and Germany, Glustin in Europe,"Glizone" and "Pioz" in India by Zydus CND and USV respectively and Zactos in Mexico by Takeda Pharmaceuticals. Actos was the tenth-best selling drug in the U.S. in 2008, with sales exceeding $2.4 billion. Its cardiovascular safety profile compares favorably with rosiglitazone (Avandia), which was withdrawn after concerns about an increased risk of cardiac events, but pioglitazone has subsequently been found to be associated with bladder tumors and has been withdrawn in some countries.

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