Cardiology

Diabetes drug may prevent recurring strokes

Pioglitazone, a drug used for type 2 diabetes, may prevent recurrent stroke and heart attacks in people with insulin resistance but without diabetes. The results of the Insulin Resistance Intervention after Stroke (IRIS) ...

Diabetes

Pioglitazone associated with lower blood leptin in diabetes

(HealthDay)—Compared to placebo, pioglitazone is associated with significantly lower blood leptin levels in patients with type 2 diabetes, according to a meta-analysis published online Dec. 1 in the Journal of Diabetes ...

Diabetes

Ipragliflozin beneficial in T2DM complicated by liver disease

(HealthDay)—For patients with type 2 diabetes and nonalcoholic fatty liver disease (NAFLD), ipragliflozin exerts beneficial effects on NAFLD and glycemic control, similar to pioglitazone, according to a study published ...

Neuroscience

Greater benefit for pioglitazone in high-risk patients post stroke

(HealthDay)—For patients after an ischemic stroke or transient ischemic attack, pioglitazone is associated with greater benefit for those at higher risk for stroke or myocardial infarction (MI), according to a study published ...

Diabetes

Pioglitazone improves left ventricular diastolic function

(HealthDay)—Pioglitazone improves whole-body and myocardial insulin sensitivity, left ventricular (LV) diastolic function, and systolic function in patients with type 2 diabetes, according to a small study published online ...

Immunology

Diabetes drug spurs host defense

Pioglitazone, a medication approved for treatment of type 2 diabetes, can help bypass genetic defects in chronic granulomatous disease to help white blood cells fight bacterial infections, according to researchers at National ...

Diabetes

Exenatide, pioglitazone effective for poorly controlled T2DM

(HealthDay)—For patients with long-standing poorly controlled type 2 diabetes mellitus (T2DM) on metformin plus a sulfonylurea, combination therapy with exenatide and pioglitazone is effective and safe, according to a study ...

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