News tagged with precursor protein
Vicious cycle: Obesity sustained by changes in brain biochemistry
With obesity reaching epidemic levels in some parts of the world, scientists have only begun to understand why it is such a persistent condition. A study in the Journal of Biological Chemistry adds substantially to the st ...
Medical research
May 16, 2013 |
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How Alzheimer's could occur: Protein spheres in the nucleus give wrong signal for cell division
A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division. In the cell culture ...
Alzheimer's disease & dementia
Apr 11, 2013 |
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Protecting against aging at the molecular level
Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...
Medical research
Apr 08, 2013 |
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Carmustine decreases amyloid beta plaques
Long term treatment by carmustine, a chemical relative of mustard gas and already used to treat some types of brain cancer, can decrease the amount of amyloid β and number of amyloid plaques in a mouse model of Alzheimer's ...
Alzheimer's disease & dementia
Mar 25, 2013 |
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No genetic clock for neuron longevity
(Medical Xpress)—People are living longer than ever before, thanks to medical and technological advances. Unfortunately, aging can be associated with a decrease in brain function. This is because, unlike ...
Neuroscience
Feb 27, 2013 |
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Modeling Alzheimer's disease using iPSCs
Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...
Alzheimer's disease & dementia
Feb 21, 2013 |
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Zebrafish reveals central regulator for development of brain histamine system
Research has shown that mutations in the psen1 gene are common in the familial forms of Alzheimer's disease, and the Presenilin-1 protein that the gene encodes is known to be involved in the cleavage of the amyloid precursor ...
Neuroscience
Feb 05, 2013 |
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'Petri dish lens' gives hope for new eye treatments
(Medical Xpress)—A cure for congenital sight impairment caused by lens damage is closer following research by scientists at Monash University.
Ophthalmology
Jan 31, 2013 |
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Study uncovers details of early stages in muscle formation and regeneration
(Medical Xpress)—Researchers at the National Institutes of Health have identified proteins that allow muscle cells in mice to form from the fusion of the early stage cells that give rise to the muscle cells.
Medical research
Jan 09, 2013 |
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Grilled, seared foods may add to waistlines, disease risk
(Medical Xpress)—A steak slapped onto a hot barbecue will leave the meat with black grill lines that add flavor and aroma, but the chemicals contained in charred, seared and fried foods may over time kick-start ...
Medical research
Dec 12, 2012 |
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New research opens new pathway for the treatment of Alzheimer's disease
Scientists from VIB and KU Leuven have discovered a new target molecule for the development of a treatment against Alzheimer's disease. There is currently no cure for this disease. Many candidate drugs fail because they also ...
Alzheimer's disease & dementia
Dec 03, 2012 |
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Discovery sheds light on Alzheimer's mystery
(Medical Xpress)—In 1906, when Alois Alzheimer discovered the neurodegenerative disease that would later be named for him, he saw amyloid-beta plaques and neurofibrillary tangles inside the brain. Several decades later, ...
Alzheimer's disease & dementia
Oct 22, 2012 |
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'Natural' protection against Alzheimer’s disease
deCODE Genetics, together with their colleagues from the pharmaceutical company Genentech, reported today in the journal Nature the discovery of a variant of the amyloid precursor protein (APP) gene that confers protection agains ...
Alzheimer's disease & dementia
Jul 11, 2012 |
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Chronic inflammation in the brain leads the way to Alzheimer's disease
Research published today in Biomed Central's open access journal Journal of Neuroinflammation suggests that chronic inflammation can predispose the brain to develop Alzheimer's disease.
Alzheimer's disease & dementia
Jul 02, 2012 |
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Understanding and treating the cognitive dysfunction of Down syndrome and Alzheimer's disease
Down syndrome (DS) is the most common genetic disorder in live born children arising as a consequence of a chromosomal abnormality. It occurs as a result of having three copies of chromosome 21, instead of the usual two. ...
Psychology & Psychiatry
Mar 01, 2012 |
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