Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study, published in Nature Communications, ...
Nov 14, 2017
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The major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the ...
Oct 21, 2013
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Alzheimer's-affected brains are riddled with amyloid plaques, protein aggregates consisting mainly of amyloid-β. However, amyloid-β is a fragment produced from a precursor protein whose normal function has remained enigmatic ...
Jan 11, 2019
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The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...
Jun 14, 2019
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(HealthDay)—Seven in 10 people with Down syndrome show evidence of dementia when they die, new research from Britain reveals.
Nov 19, 2018
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Alzheimer's disease (AD) can be divided into rare early onset familial AD (fAD) and common late onset sporadic AD (sAD) that impairs the memory and cognitive functions of older people worldwide.
Apr 14, 2023
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Researchers from the Université Laval Faculty of Medicine and CHU de Québec–Université Laval Research Center have successfully edited the genome of human cells grown in vitro to introduce a mutation providing protection ...
Feb 10, 2022
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Around 80% of people with Down syndrome develop Alzheimer's disease, often when they are between 40 and 50 years old. A study led by Lund University in Sweden has shown that a simple blood test can detect Alzheimer's disease ...
Aug 24, 2022
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(Medical Xpress)—People are living longer than ever before, thanks to medical and technological advances. Unfortunately, aging can be associated with a decrease in brain function. This is because, unlike other cells in ...
Researchers at the Wellcome Trust Sanger Institute have discovered two proteins that are essential for the fusion of muscle cells to build muscle fibres. Their discovery might help us better understand and treat illnesses ...
Dec 13, 2011
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