Diabetes

New approach for regenerative diabetes therapy

The marker Flattop subdivides the insulin-producing beta cells of the pancreas into those that maintain glucose metabolism and into immature cells that divide more frequently and adapt to metabolic changes. This could provide ...

Oncology & Cancer

Aggressiveness of acute myeloid leukemia elucidated

Antoine Peters and colleagues at the Basel University Children's Hospital (UKBB) have discovered why acute leukemias with the same genetic abnormality vary in their aggressiveness based on their cellular origin. They found ...

Medical research

Expansion of kidney progenitor cells toward regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National ...

Alzheimer's disease & dementia

Dysfunctional endosomes are early sign of neurodegeneration

Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells ...

Alzheimer's disease & dementia

Researchers work to block harmful behavior of key Alzheimer's enzyme

Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer's disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. ...

Genetics

Can gene therapy provide a breakthrough in Alzheimer's disease?

Therapeutic gene transfer to specific brain regions in animal models of Alzheimer's disease has uncovered multiple potential treatment approaches that deserve to be considered as candidates for clinical applications, according ...

Neuroscience

Myelin cells swing along blood vessels to traverse the brain

The cells that create myelin, a fatty material that insulates nerve fibers in the brain's white matter, migrate into the developing brain by climbing and swinging on blood vessels, according to new research led by UC San ...

Medical research

Proto-teeth migrate along the developing jaw

Smile! For the first time, researchers have captured on video how teeth find their way to the right spot in the jaw to give you that winning grin. The research, led by scientists at UC San Francisco, showed in mice that molar ...

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