The spread of prions to the brain does not occur by direct transmission across the blood-brain barrier, according to a study published November 29 in the open-access journal PLOS Pathogens by Annika Keller and Adriano Aguzzi ...
Nov 29, 2018
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The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. ...
Nov 18, 2022
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Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives, according to a new report ...
Aug 2, 2019
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Researchers from McGovern Medical School at The University of Texas Health Science Center at Houston have discovered that the symptoms of diabetes can be induced by a misfolded form of a pancreatic protein. The findings, ...
Aug 1, 2017
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A new study has shed light on the mechanisms underlying the progression of prion diseases and identified a potential target for treatment.
Sep 21, 2018
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Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein particles often go undetected ...
Jan 22, 2019
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A new University of Toronto study sheds light on how protein strains vary in the brains of those affected by progressive neurodegenerative diseases like Parkinson's, suggesting the need for patient-specific medicines.
Dec 4, 2019
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Scientists from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), report that they have developed a method—10,000 times more sensitive than other methods—to ...
May 9, 2011
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Chronic wasting disease (CWD)—an infectious disease caused by prions—affects North American elk and deer, but has not been observed in humans. Using a mouse model that expresses an altered form of the normal human prion ...
Feb 23, 2015
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(Medical Xpress) -- Many of us are familiar with prion disease from its most startling and unusual incarnations—the outbreaks of “mad cow” disease (bovine spongiform encephalopathy) that created a crisis in ...
Aug 10, 2012
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