Gene sequencing project identifies potential drug targets in common childhood brain tumor
Researchers studying the genetic roots of the most common malignant childhood brain tumor have discovered missteps in three of the four subtypes of the cancer that involve genes already targeted for drug development.
Cancer
Jun 20, 2012 |
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Research shows new prognosis tool for deadly brain cancer
A diagnosis of glioblastoma multiforme (GBM) is generally a death sentence, but new research from the University of Wisconsin-Madison lab of Dr. John Kuo shows that at least one subtype is associated with a longer life expectancy. ...
Cancer
Jun 20, 2012 |
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RLIP76 contributes to pancreatic cancer cell resistance to chemotherapy and radiation
Researchers at the City of Hope Comprehensive Cancer Center have not only identified a protein that allows pancreatic cancer cells to resist therapy but also developed a way to block it, according to results presented at ...
Cancer
Jun 19, 2012 |
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A new indicator for breast cancer relapse identified
Researchers at the IMIM (Institut de Recerca Hospital del Mar) have proven that the absence of the 14-3-3 protein sigma in breast cancer cells is directly associated with these cells' capacity to activate the signalling of ...
Cancer
Jun 19, 2012 |
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Mutations in JAK3 gene identified in subtype of lymphoma provide potential drug target
A substantial proportion of NK/T-cell lymphomas harbor Janus Kinase 3 gene mutations. Patients with these lymphomas might benefit from treatment with a Janus Kinase inhibitor according to a study published in Cancer Discovery, a jour ...
Cancer
Jun 15, 2012 |
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Genetic markers hope for new brain tumor treatments
Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.
Cancer
Jun 15, 2012 |
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Haematopoietic stem cell transplantation increases survival in systemic sclerosis patients
Initial results from an international, investigator-initiated, open label phase III trial were presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism. Data indicate that haematopoietic stem ...
Arthritis & Rheumatism
Jun 07, 2012 |
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Combination treatment with lapatinib and pazopanib doesn't improve outcomes for patients with IBC
Inflammatory breast cancer is a very aggressive type of cancer associated with early metastasis and poor survival rates, and the prognosis is even worse for patients with tumors expressing the ErbB2 receptor. The ErbB2-inhibiting ...
Cancer
Jun 01, 2012 |
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Listening in, researchers learn about end-of-life communication
What is the best way to talk to someone about prognosis and quality of life when serious illness strikes? It turns out that no one had studied that question through direct observation, until the University of Rochester Medical ...
Other
May 31, 2012 |
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Men and women receive different fertility advice following cancer diagnosis
There are significant gaps in the information women receive about their future fertility following cancer diagnosis, suggests a new paper published today (30 May) in BJOG: An International Journal of Obstetrics and Gynaecology.
Obstetrics & gynaecology
May 30, 2012 |
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Skp2 activates cancer-promoting, glucose-processing Akt
HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.
Cancer
May 25, 2012 |
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New protein signature of breast cancer progression identified
A protein signature that predicts overall survival in breast cancer patients has been uncovered in the most comprehensive survey of protein expression patterns in breast cancer progression to date.
Cancer
May 22, 2012 |
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Revised glioblastoma classification should improve patient care
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors.
Cancer
May 16, 2012 |
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Researchers identify genetic mutation causing rare form of spinal muscular atrophy
Scientists have confirmed that mutations of a gene are responsible for some cases of a rare, inherited disease that causes progressive muscle degeneration and weakness: spinal muscular atrophy with lower extremity predominance, ...
Neuroscience
May 10, 2012 |
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Researchers use genomics to identify a molecular-based treatment for a viral skin cancer
Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...
Cancer
May 09, 2012 |
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