News tagged with programmed cell death

Drug targets hard-to-reach leukemia stem cells responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms ...

Cancer created Jan 17, 2013 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Autoimmune disease—retraining white blood cells

Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.

Immunology created Dec 17, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Unexpected discovery highlights new role for cell death regulator

An unexpected discovery of how the body controls cell death has revealed a potential new therapeutic target.

Medical research created Jun 14, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Worm 'cell death' discovery could lead to new drugs for deadly parasite

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's ...

Medical research created Sep 28, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Hopes that new substance will induce cancer cell suicide

(Medical Xpress)—The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells ...

Cancer created Sep 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...

Cancer created Jan 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Molecule shows effectiveness against drug-resistant myeloma

A molecule that targets the cell's machinery for breaking down unneeded proteins can kill multiple myeloma cancer cells resistant to the frontline drug Velcade, researchers at Dana-Farber Cancer Institute have found.

Cancer created Sep 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Obesity promotes prostate cancer by altering gene regulation

Prostate cancer is one of the most common cancers in men and early treatment is usually very successful. However, like other cancers, obesity increases the risk of aggressive prostate disease. New research, published in BioMed ...

Cancer created Sep 24, 2012 | popularity not rated yet | comments 0

A novel oncogenic network specific to liver cancer initiation

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, ...

Cancer created Oct 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Researchers find important 'target' playing role in tobacco-related lung cancers

Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce ...

Cancer created Feb 09, 2012 | popularity 5 / 5 (1) | comments 0

Indian plant could play key role in death of cancer cells

Scientists at the Georgia Regents University Cancer Center have identified an Indian plant, used for centuries to treat inflammation, fever and malaria, that could help kill cancer cells.

Cancer created Feb 14, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

New tool determines leukemia cells' 'readiness to die,' may guide clinical care

Researchers at Dana-Farber Cancer Institute have developed a novel method for determining how ready acute myeloid leukemia (AML) cells are to die, a discovery that may help cancer specialists to choose treatments option more ...

Cancer created Oct 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancer

Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively ...

Cancer created Apr 09, 2013 | popularity 4 / 5 (1) | comments 0

Scientists discover new method of predicting response to chemotherapy in bowel cancer

Scientists at the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have developed a new method of predicting which patients with bowel (colorectal) cancer will respond effectively to chemotherapy. The results ...

Cancer created Jan 18, 2013 | popularity not rated yet | comments 0

Cell death mystery yields new suspect for cancer drug development

A mysterious form of cell death, coded in proteins and enzymes, led to a discovery by UNC researchers uncovering a prime suspect for new cancer drug development.

Cancer created Sep 13, 2012 | popularity 5 / 5 (3) | comments 0

Programmed cell death

Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

For more information about Programmed cell death, read the full article at Wikipedia.
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