Researchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzheimer's disease (AD). In a paper, "Proteomics of brain, CSF, and blood identifies molecular ...
A new study published in Nature Genetics led by the Mead Group in the Radcliffe Department of Medicine has demonstrated a previously unknown effect of chronic inflammation on TP53-mutant hematopoietic stem cells.
Sep 8, 2023
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253
Essentially all human tissues and organs have the capacity to heal, to renew cells which are damaged or killed. In this context, the human brain behaves fundamentally differently. The vast majority of nerve cells are created ...
Oct 24, 2022
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101
Science has long known that recovery from experimental heart attacks is improved by injection of a mixture of heart muscle cells, endothelial cells and smooth muscle cells, yet results have been limited by poor engraftment ...
Sep 29, 2020
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Researchers may have found a way to press pause on spinal disc injuries, giving doctors more time to treat them before worse issues develop. The Penn Medicine-led team discovered that cells in the outer region of spinal discs ...
Oct 14, 2019
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Researchers at the University of Alberta have discovered a unique process of brain cell death that affects the cells that are most vulnerable in multiple sclerosis (MS).
Jun 12, 2018
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Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death. Thanks to the advances ...
Sep 22, 2017
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The immune system's killer cells deliver a tightly controlled, 3-phase knockout punch that kills intracellular parasites through a novel pathway that an international team led by researchers from the Program in Cellular and ...
Jan 19, 2016
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Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown for the first time how a previously unknown process works to promote infection in a number of dangerous viruses, including dengue, West ...
Nov 23, 2015
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Scientists at The Scripps Research Institute (TSRI) have discovered a new role for an enzyme involved in cell death. Their study shows how the enzyme, called RIPK3, relays signals between the cell's mitochondria "powerhouses" ...
Sep 18, 2015
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Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.
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