News tagged with programmed cell death

Indian plant could play key role in death of cancer cells

Scientists at the Georgia Regents University Cancer Center have identified an Indian plant, used for centuries to treat inflammation, fever and malaria, that could help kill cancer cells.

Cancer created Feb 14, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast

Diabetes drug could hold promise for lung cancer patients

Ever since discovering a decade ago that a gene altered in lung cancer regulated an enzyme used in therapies against diabetes, Reuben Shaw has wondered if drugs originally designed to treat metabolic diseases ...

Cancer created Jan 29, 2013 | popularity not rated yet | comments 0 | with audio podcast

Drug targets hard-to-reach leukemia stem cells responsible for relapses

Researchers at the University of California, San Diego School of Medicine have discovered that hard-to-reach, drug-resistant leukemia stem cells (LSCs) that overexpress multiple pro-survival protein forms ...

Cancer created Jan 17, 2013 | popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Autoimmune disease—retraining white blood cells

Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.

Immunology created Dec 17, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

A protein's role in helping cells repair DNA damage

(Medical Xpress)—In a new study, University at Buffalo scientists describe the role that a protein called TFIIB plays in helping cells repair DNA damage, a critical function for preventing the growth of tumors.

Medical research created Nov 01, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New tool determines leukemia cells' 'readiness to die,' may guide clinical care

Researchers at Dana-Farber Cancer Institute have developed a novel method for determining how ready acute myeloid leukemia (AML) cells are to die, a discovery that may help cancer specialists to choose treatments option more ...

Cancer created Oct 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

A novel oncogenic network specific to liver cancer initiation

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, ...

Cancer created Oct 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Hopes that new substance will induce cancer cell suicide

(Medical Xpress)—The p53 gene plays a key role in the prevention of cancer, by blocking cell growth and triggering programmed cell death or apoptosis. If, however, p53 has mutated and become defective, the cancer cells ...

Cancer created Sep 18, 2012 | popularity not rated yet | comments 0 | with audio podcast

Molecule shows effectiveness against drug-resistant myeloma

A molecule that targets the cell's machinery for breaking down unneeded proteins can kill multiple myeloma cancer cells resistant to the frontline drug Velcade, researchers at Dana-Farber Cancer Institute have found.

Cancer created Sep 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Unexpected discovery highlights new role for cell death regulator

An unexpected discovery of how the body controls cell death has revealed a potential new therapeutic target.

Medical research created Jun 14, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Blocking DNA: HDAC inhibitor targets triple negative breast cancer

The histone de-acetylase (HDAC) inhibitor panobinostat is able to target and destroy triple negative breast cancer, reveals a new study published in BioMed Central's open access journal Breast Cancer Research. Researchers from T ...

Cancer created May 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study identifies trigger for alternate reproduction of HIV-related cancer virus

A research team led by Children's National Medical Center has identified a trigger that causes latent Kaposi's sarcoma-associated herpesvirus (KSHV) to rapidly replicate itself. KSHV causes Kaposi's sarcoma, primary effusion ...

Cancer created Apr 17, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Melatonin delays onset, reduces deaths in mouse model of Huntington's disease

Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and ...

Neuroscience created Oct 11, 2011 | popularity 4.7 / 5 (3) | comments 0 | with audio podcast

Worm 'cell death' discovery could lead to new drugs for deadly parasite

Researchers from the Walter and Eliza Hall Institute have for the first time identified a 'programmed cell death' pathway in parasitic worms that could one day lead to new treatments for one of the world's ...

Medical research created Sep 28, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Latest research shows how cancer cells react to chemotherapy

EU-funded researchers have made good progress in understanding how cancer cells can sometimes resist the effects of chemotherapy. This new knowledge will move forward the development of increasingly effective ...

Cancer created Jul 14, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Programmed cell death

Programmed cell-death (or PCD) is death of a cell in any form, mediated by an intracellular program. In contrast to necrosis, which is a form of cell-death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process which generally confers advantage during an organism's life-cycle. PCD serves fundamental functions during both plant and metazoa (multicellular animals) tissue development.

For more information about Programmed cell death, read the full article at Wikipedia.
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