Oncology & Cancer

A novel pathway to target colorectal cancer

While the emergence of precision medicine and immunotherapy has greatly improved outcomes for patients with colorectal cancer, new approaches are still needed for patients with late-stage disease who do not respond to these ...

Diabetes

How the body protects itself from type 2 diabetes

A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...

Oncology & Cancer

Searching out pancreatic cancer risk

A prospective study by Wei Zheng, Ph.D., M.D., and colleagues delivers the first direct epidemiological evidence that increased production of a chemical compound called prostaglandin E2 (PGE2), as measured by metabolites ...

Medical research

Researchers confirm molecule's role in kidney formation

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a ...

Medical research

Scientists find cell fate switch that decides liver, or pancreas?

Harvard stem cell scientists have a new theory for how stem cells decide whether to become liver or pancreatic cells during development. A cell's fate, the researchers found, is determined by the nearby presence of prostaglandin ...

Medical research

Studying marrow, researchers accelerate blood stem cells

(Medical Xpress)—University of Rochester Medical Center scientists are testing a new approach to speed a patient's recovery of blood counts during a vulnerable period after a stem-cell transplant, according to a study published ...

Diseases, Conditions, Syndromes

Maintaining fluid and electrolyte balance in the kidney

Distal renal tubular acidosis (dRTA) develops in response to the loss of acid secretion by α-intercalated cells in the kidney. The inability to remove acid from the body results in low blood potassium levels (hypokalemia), ...

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