Boosting the activity of a vitamin-sensitive cell adhesion pathway has the potential to counteract the muscle degeneration and reduced mobility caused by muscular dystrophies, according to a research team led by scientists ...
Oct 23, 2012
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Proteins are sometimes described as the building blocks of life; inside cells, proteins associate into large macromolecular complexes, consortia of proteins that cooperate to perform specific functions. A large number of ...
May 1, 2019
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Amyloid fibrils play a crucial role in neurodegenerative illnesses. Scientists from Heinrich Heine University Düsseldorf (HHU) and Forschungszentrum Jülich have now been able to use cryo-electron microscopy (cryo-EM) to ...
Aug 21, 2019
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An immune response that likely evolved to help fight infections appears to be the mechanism that drives human immunodeficiency virus (HIV) into a latent state, lurking in cells only to erupt anew, researchers at Duke Health ...
Nov 14, 2022
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In breast cancer, metastasis rather than the primary tumor is the cause of death. A lack of oxygen in the tumor cells promotes this metastasis, accompanied by a reprogramming of the cell's metabolism. Ph.D. candidate Qiuyu ...
Mar 6, 2023
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The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires ...
Jul 4, 2022
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161
During brain development, neurons have to migrate long distances through complex environments until they reach their final destination. In order to find guidance, they must establish several interactions—which are still ...
Oct 18, 2022
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Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The ...
Oct 21, 2011
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A team of international researchers has identified a process that functions like a rheostat to dial up cell division by dislodging a tumor suppressor protein that serves as an off switch. The mechanism offers insight into ...
May 1, 2019
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Researchers have long sought to explain precisely how the most common genetic mutation linked to both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia causes the death of nerve cells. Now, Johns Hopkins Medicine ...
Sep 3, 2020
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