News tagged with protein interaction
Scientists identify important regulator for synapse stability and plasticity
(Medical Xpress)—Using the fruit fly as a model organism, neurobiologists from the Friedrich Miescher Institute for Biomedical Research have identified the L1-type CAM neuroglian as an important regulator ...
Neuroscience
Apr 25, 2013 |
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Highly lethal Ebola virus has diagnostic Achilles' heel for biothreat detection, scientists say
By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute's highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in ...
Medical research
Apr 05, 2013 |
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Researchers design small molecule to disrupt cancer-causing protein
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer. This development could impact the treatment of several ...
Cancer
Mar 26, 2013 |
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Did evolution give us inflammatory disease?
In new research published on March 21, 2013 in the online issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital (BWH) demonstrate that some variants in our genes that contribute to a p ...
Genetics
Mar 21, 2013 |
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Research illuminates molecular mechanism for why stimulating environment may protect against Alzheimer's disease
"Use it or lose it." The saying could apply especially to the brain when it comes to protecting against Alzheimer's disease. Previous studies have shown that keeping the mind active, exercising and social interactions may ...
Alzheimer's disease & dementia
Mar 06, 2013 |
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Providing brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study cell-cell ...
Medical research
Jan 25, 2013 |
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Cancer suppressor gene links metabolism with cellular aging
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Cancer
Jan 13, 2013 |
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The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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Researchers uncover a crucial link between protein synthesis and autism spectrum disorders
Researchers from McGill University and the University of Montreal have identified a crucial link between protein synthesis and autism spectrum disorders (ASD), which can bolster new therapeutic avenues. Regulation of protein ...
Autism spectrum disorders
Nov 21, 2012 |
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Charting the SH2 pool
New research published in BioMed Central's open access journal Cell Communication and Signaling describes a large set of interactions (interactome) which maps the range of phosphotyrosine (pTyr)-dependent interactions with S ...
Medical research
Sep 13, 2012 |
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New target found for cancers resistant to Iressa and Herceptin
A more-sensitive method to analyze protein interactions has uncovered a new way that cancer cells may use the cell-surface molecule HER3 to drive tumor progression following treatment with HER1 and HER2 inhibitors.
Cancer
Sep 04, 2012 |
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Cancer gene family member functions key to cell adhesion and migration
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While ...
Cancer
Aug 30, 2012 |
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Study details power of new chip to diagnose disease, analyze protein interactions
Researchers at the Stanford University School of Medicine and Intel Corp. have collaborated to synthesize and study a grid-like array of short pieces of a disease-associated protein on silicon chips normally used in computer ...
Medical research
Aug 20, 2012 |
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Making sense out of the biological matrix of bipolar disorder
The more that we understand the brain, the more complex it becomes. The same can be said about the genetics and neurobiology of psychiatric disorders. For "Mendelian" disorders, like Huntington disease, mutation of a single ...
Psychology & Psychiatry
Aug 20, 2012 |
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New ways viruses affect human immune response discovered
(Medical Xpress) -- New ways that viruses manipulate the human immune response have been revealed in a research paper just published in Nature involving TCD scientists. Dr Orla Mulhern and Professor Andrew Bowie, School of Bio ...
Immunology
Aug 03, 2012 |
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