Scientists have shown exactly how mutations in two different genes coordinate to drive the development of malignant lung tumors, according to a new report in the open-access journal eLife.
Aug 27, 2019
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The basic unit of all living things is the cell—and the human body contains tens of trillions of them. Cancer can be triggered by the abnormal growth and division of just one of these, which goes on to form a lump or tumor.
Aug 16, 2019
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Prostate cancer represents a major health challenge and there is currently no effective treatment once it has advanced to the aggressive, metastatic stage. A new has revealed a key cellular mechanism that contributes to aggressive ...
Jul 2, 2019
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The protein STK17A (serine threonine kinase 17A) appears to play roles in various cancer types. It can be oncogenic or tumor suppressive, depending on the cancer, but its role in colorectal cancer has not been established.
Mar 1, 2019
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AICAr (5-amino-4-imidazolecarboxamide riboside, also called Acadesine) has been found to inhibit cell proliferation and has cytotoxic potential for childhood acute lymphoblastic leukemia (ALL) cells. Much of the drug's cytotoxic ...
Jan 31, 2019
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Chronic kidney disease (CKD), an affliction characterized by progressive loss of kidney function, affects millions of people worldwide and is associated with multi-organ damage, cardiovascular disease and muscle wasting. ...
Dec 10, 2018
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A multidisciplinary research team at Aarhus University has provided fundamental new insight into the mechanism of the medical drug dimethyl fumarate, which is the active component of important treatments for multiple sclerosis ...
Nov 1, 2018
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The circadian cycle, a long-studied factor controlling human sleep cycles, actually has two forms, one that keeps a key protein stable, and another that promotes its degradation.
Jul 12, 2018
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Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumour, while another gene promotes the tumour. This is shown in a new dissertation at Umeå University, ...
May 24, 2018
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Protein researchers from the Novo Nordisk Foundation Center for Protein Research at the University of Copenhagen have used mass spectrometry-based proteomics to uncover a number of proteins that could play a critical role ...
May 15, 2018
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