News tagged with protein kinase

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New therapeutic approach for advanced lung disease

Researchers have demonstrated the potential of a new class of drugs for the treatment of refractory chronic obstructive pulmonary disease (COPD). Incurable to date, the disease is one of the most frequent causes of death ...

21 hours ago
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Protein kinase

A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.

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