Serine racemase (SRR) is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate. Though already well characterized, a team of researchers led ...
Jan 29, 2020
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Can pyruvate, the end product of glycolysis, help improve cardiovascular function in children who have cardiopulmonary bypass surgery and suffer from low cardiac output syndrome (LCOS)? This question is one that Rafael Jaimes, ...
Dec 19, 2018
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Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection.
Jul 9, 2015
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An enzyme found in all living things could hold the key to combatting deadly diseases such as sleeping sickness, a study suggests.
Sep 24, 2014
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Researchers at the University at Buffalo, led by Dr. Mulchand Patel and also at Lawson Health Research Institute and Western Ontario, London, Canada, led by Dr. David Hill, collaboratively evaluated the role of the mitochondrial ...
Aug 5, 2014
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Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments in mice, ...
Dec 19, 2012
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Cancer cells grow fast. That's an essential characteristic of what makes them cancer cells. They've crashed through all the cell-cycle checkpoints and are continuously growing and dividing, far outstripping our normal cells. ...
Oct 31, 2012
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A metabolic protein that nourishes cancer cells also activates tumor-promoting genes by loosening part of the packaging that entwines DNA to make up chromosomes, a team led by scientists at The University of Texas MD Anderson ...
Aug 16, 2012
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Cancer cells maintain their life-style of extremely rapid growth and proliferation thanks to an enzyme called PK-M2 (pyruvate kinase M2) that alters the cells' ability to metabolize glucose – a phenomenon known as the ...
Nov 2, 2011
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Cancer cells are well known for their altered metabolisms, which may help them generate the energy they need for rapid growth. Using an emerging imaging technology, researchers reporting in the July Cell Metabolism, a Cell ...
Jul 5, 2011
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