Medical research

Nanobody-drug conjugates hijack the human vitamin B12 uptake route

A major challenge in cancer therapy is selectively targeting cancer cells over healthy ones. A recent study by the Locher group (IMBB) describes the development of camelid single-domain antibodies (nanobodies) that selectively ...

Medical research

Nicotine works inside cells to reinforce addiction: study

When a person takes a puff on a cigarette, nicotine floods into the brain, latching onto receptors on the surface of neurons and producing feelings of happiness. But nicotine does not simply stay on the surface of cells—the ...

Diseases, Conditions, Syndromes

Coronary heart disease risk higher with COPD

Patients with chronic obstructive pulmonary disease (COPD) are more likely to have coronary heart disease (CHD), but no specific phenotypes have a higher risk, according to a study published online April 27 in PLOS ONE.

Oncology & Cancer

A leap forward in research on CAR T cell therapy

In cancer immunotherapy, cells in the patient's own immune system are activated to attack cancer cells. CAR T cell therapy has been one of the most significant recent advances in immunotherapies targeted at cancer.

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