Oncology & Cancer

Old drug may have new tricks for fighting cancer

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude ...

Oncology & Cancer

Novel mechanism that protects from glioblastoma identified

A group of researchers at the Spanish National Cancer Research Centre (CNIO) have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 ...

Medical research

Team reveals molecular pathway of weight-controlling hormone

Scientists at NGM Bio have revealed deep insights into the role that a little-understood human hormone plays in regulating body weight. Named Growth and Differentiation Factor 15 (GDF15), this hormone is typically active ...

Medical research

Obese inducing brain mechanism

Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...

Oncology & Cancer

Mathematical modeling could help with personalized cancer care

A new study from the University of Southern California could pave the way for improving personalised lung cancer care and treatment.The research used mathematical modelling to examine if there was a link between the molecular ...

Psychology & Psychiatry

Cause of obsessive-compulsive disorder discovered

An overactive molecular signal pathway in the brain region of the amygdala can lead to obsessive-compulsive disorder (OCD). A research team from Würzburg has established this connection.

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