Studies show increasing evidence that androgen drives breast cancer
Estrogen and progesterone receptors, and the gene HER2 – these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.
Cancer
Apr 10, 2013 |
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Researchers identify critical metabolic alterations in triple-negative breast cancer cells
Researchers at Fox Chase Cancer Center have identified a host of small molecules critical to metabolism in cells of triple-negative breast cancer—one of the least understood groups of breast cancer. These molecules, called ...
Cancer
Apr 09, 2013 |
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Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancer
Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively ...
Cancer
Apr 09, 2013 |
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New target plus new drug equals death of melanoma cells
Collaborative research presented by the University of Colorado Cancer Center, the University of North Carolina at Chapel Hill, Harvard Medical School and the University of Pittsburgh, at the American Association for Cancer ...
Cancer
Apr 09, 2013 |
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A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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Certain breast cancer patients may benefit from combined HER2 targeted therapy without chemotherapy
Is the era of targeted therapy for breast cancer at hand? It could be, said experts at the Lester and Sue Smith Breast Center at Baylor College of Medicine – at least for a certain population of women.
Cancer
Apr 08, 2013 |
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Study finds that hot and cold senses interact
A study from the University of North Carolina School of Medicine offers new insights into how the nervous system processes hot and cold temperatures. The research led by neuroscientist Mark J. Zylka, PhD, ...
Neuroscience
Apr 08, 2013 |
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Moving cells with light holds medical promise
Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion ...
Medical research
Apr 08, 2013 |
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Paragazole excels in preclinical models of triple-negative breast cancer
Breast cancers that lack estrogen receptors are more difficult to treat than ER+ cancers. Research presented at the AACR Annual Meeting 2013 demonstrates an investigational drug, Paragazole, that makes triple-negative ...
Cancer
Apr 08, 2013 |
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Bird flu mutation study offers vaccine clue
(Medical Xpress)—Scientists have described small genetic changes that enable the H5N1 bird flu virus to replicate more easily in the noses of mammals.
Diseases, Conditions, Syndromes
Apr 08, 2013 |
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Cellular gatekeepers do more than open doors for drugs, study finds
(Medical Xpress)—The cellular gatekeepers that escort the most common pharmaceuticals into our cells continue to work within the cells as well, according to a UC San Francisco discovery that could transform drug design ...
Medical research
Apr 08, 2013 |
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Immunotherapy showed promising antileukemia activity in pediatric patients
Researchers using patients' own immune cells in an immunotherapy approach called "anti-CD19 chimeric antigen receptor (CAR) T-cell therapy," achieved responses in children whose acute lymphocytic leukemia (ALL) had returned ...
Cancer
Apr 07, 2013 |
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Do cells in the blood, heart and lungs smell the food we eat?
In a discovery suggesting that odors may have a far more important role in life than previously believed, scientists have found that heart, blood, lung and other cells in the body have the same receptors for sensing odors ...
Medical research
Apr 07, 2013 |
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Genome wide study identifies genetic variants associated with childhood obesity
Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.
Genetics
Apr 07, 2013 |
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Engineered T cells kill tumors but spare normal tissue in an animal model
The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...
Cancer
Apr 07, 2013 |
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