Scientists identify Achilles heel of lung cancer protein
Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
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Researchers have shown for the first time that a crucial interface in a protein that drives cancer growth could act as a target for more effective treatments.
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The hormone insulin controls many cellular processes and adapts them to the body's current energy supply. One of the insulin-regulated processes is the quality control of mitochondria in neurons, Angelika Harbauer and her ...
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The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
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Polyphenols are powerful plant metabolites known for their antioxidant properties, offering potential health benefits and protection against various diseases. With over 8,000 identified varieties, these substances are found ...
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A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical ...
Mar 15, 2024
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T cells are often called "assassins" or "killers" because they can orchestrate and carry out missions to hunt down bacteria, viruses, and cancer cells throughout the body. Mighty as they may be, recent research has shown ...
Mar 15, 2024
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Making a personalized T cell therapy for cancer patients currently takes at least six months; scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have shown that the laborious ...
Mar 15, 2024
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Scientists have developed an improved technique for reading the genetic material associated with the body's immune response to cancer, making it possible to study tissue samples that have been stored in archives for decades.
Mar 15, 2024
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Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain ...
Mar 13, 2024
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All living cells teem with ribonucleic acid (RNA), molecules that relay genetic messages to keep cells functioning. But these necessary molecules can also set off cellular alarms. The long twisted-together strands of RNA ...
Mar 11, 2024
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In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a "ligand," and may be a peptide (such as a neurotransmitter), a hormone, a pharmaceutical drug, or a toxin, and when such binding occurs, the receptor undergoes a conformational change which ordinarily initiates a cellular response. However, some ligands merely block receptors without inducing any response (e.g. antagonists). Ligand-induced changes in receptors result in physiological changes which constitute the biological activity of the ligands.
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