Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill ...
Sep 7, 2022
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105
An unexpected trick in cancer's playbook may fool an important component of our immune systems into knocking down our natural defenses against solid tumors.
May 13, 2022
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70
Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.
Apr 19, 2022
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86
WEHI researchers have found a way to supercharge immune cells that could enable them to clear disease and infections faster.
Apr 14, 2022
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56
Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation. Infusions of purified IL-27 regulatory ...
Dec 2, 2021
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38
Activating the immune system to battle infections or cancers depends on more than detecting the threat. The immune system must also detect whether its cells have sufficient nutrients to fuel the immune response.
Nov 19, 2021
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64
A two-arm molecule can effectively deplete cancer-protecting cells inside tumors, allowing the immune system to fight off tumors without becoming overactive. The finding, published online in Science Translational Medicine, ...
Aug 11, 2021
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492
Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to ...
Feb 24, 2021
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67
Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism ...
Feb 24, 2021
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187
A paper published today in Nature shows how chemicals in the areas surrounding tumors—known as the tumor microenvironment—subvert the immune system and enable cancer to evade attack. These findings suggest that an existing ...
Feb 15, 2021
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