Neuroscience

Cocaine relapse is reversed with BDNF microinjections in the brain

Cocaine relapse was significantly reduced in a preclinical model when brain-derived neurotropic factor (BDNF) was applied to the nucleus accumbens deep in the brain immediately before cocaine-seeking behavior, report investigators ...

Health

Ex-smokers crave lost identity, study shows

Ex-smokers may not be able to resist lighting up again in order to recover a sense of 'who they are'– according to new research from the University of East Anglia.

Medications

Opioid use may affect treatment for alcohol dependence

New research indicates that opioid misuse and the use of cannabis and other drugs may compromise the effectiveness of treatments for alcohol use disorder. In an Alcoholism: Clinical and Experimental Research study, individuals ...

Oncology & Cancer

The four survival strategies of tumor cells in childhood cancer

Cancer cells in children tend to develop by following four main trajectories—and two of them are linked to relapse of the disease, according to a study led by Lund University in Sweden, now published in Nature Genetics. ...

Psychology & Psychiatry

Relapse in major depression linked to brain cortical changes

(HealthDay)—For patients with major depressive disorder (MDD), relapse is associated with brain cortical changes over two years, according to a study published online March 28 in JAMA Psychiatry.

Oncology & Cancer

Molecular minimal disease in remission predicts AML relapse

(HealthDay)—The detection of molecular minimal residual disease is associated with increased relapse rates in acute myeloid leukemia (AML), according to a study published in the March 29 issue of the New England Journal ...

Psychology & Psychiatry

Non-psychoactive cannabis ingredient could help addicts stay clean

A preclinical study in rats has shown that there might be value in using a non-psychoactive and non-addictive ingredient of the Cannabis sativa plant to reduce the risk of relapse among recovering drug and alcohol addicts. ...

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