Oncology & Cancer
Predicting cancer patient response to drugs that block DNA repair
Researchers have identified genetic tests that predict which cancer patients may benefit from the drugs in combination with chemotherapy.
Nov 6, 2023
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News tagged with repair cells
Oncology & Cancer
New strategy attacks treatment-resistant lymphomas
A surprising mechanism that makes some cancers treatment-resistant has been discovered by Weill Cornell Medicine and NewYork-Presbyterian investigators. The mechanism, which involves the shuttling of messenger RNAs (mRNAs) ...
Nov 2, 2023
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Genetics
Find-and-replace genome editing with CRISPR: A promising therapeutic strategy
Severe combined immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development. SCID can also affect B-cell and natural killer ...
Oct 27, 2023
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Medical research
A comprehensive proteogenomic dataset to help cancer researchers unravel molecular mysteries
The National Institutes of Health is releasing a comprehensive dataset that standardizes genomic, proteomic, imaging, and clinical data from individual studies of more than 1,000 tumors across 10 cancer types. Researchers ...
Aug 14, 2023
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Medical research
Tapping into regeneration: New paths to repairing brain injury discovered in fruit flies
Researchers at Duke-NUS Medical School have discovered the regenerative capabilities of injured cellular protrusions from dormant neural stem cells (NSCs) in fruit flies. Published in Developmental Cell, the findings establish ...
Aug 8, 2023
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Genetics
Biologist explains why no two people or cells age the same way, and what this means for anti-aging interventions
You likely know someone who seems to age slowly, appearing years younger than their birth date suggests. And you likely have seen the opposite—someone whose body and mind seem much more ravaged by time than others. Why ...
Jul 7, 2023
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Genetics
Cellular senescence involves gene repression through p53-p16/RB-E2F-DREAM complex
A new research paper titled "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex" has been published in Aging.
Jun 13, 2023
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Genetics
Researchers assemble comprehensive atlas of gene mutations in human tissue
Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled—a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease. It is ...
Apr 13, 2023
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Medical research
Mucus-based gel improves bone graft results and promotes healing
Molecules from mucus can be used to produce synthetic bone graft material and help with the healing of larger bone loss, a new study found.
Feb 7, 2023
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Immunology
Scientists reveal the role of immune progenitor cells in the repair of inflamed intestinal tissue
The human body contains an array of coexisting commensal microbes, primarily gut bacteria, which have been linked to the regulation of hematopoiesis, or the production of blood and its components (including immune cells).
Dec 8, 2022
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