News tagged with resistance mechanisms

Weight gain induced by high-fat diet increases active-period sleep and sleep fragmentation

Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that prolonged exposure to ...

Health Jul 10, 2012 | not rated yet | 0

Cell differentiation as a novel strategy for the treatment of an aggressive type of skin cancer

Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc. However, ...

Cancer Jul 09, 2012 | not rated yet | 0

Researchers find success with new immune approach to fighting some cancers

A national research collaboration of senior researchers, including a researcher from Moffitt Cancer Center, has found that 20 to 25 percent of "heavily pre-treated" patients with a variety of cancers who enrolled in a clinical ...

Cancer Jun 13, 2012 | 5 / 5 (1) | 0 |

Culprit behind unchecked angiogenesis identified

German researchers unravel a critical regulatory mechanism controlling blood vessel growth that might help solve drug resistance problems in the future.

Medical research Mar 29, 2012 | 3 / 5 (1) | 0 |

Staph sepsis increases mortality in preterm infants

(HealthDay) -- Only about 1 percent of very low birth weight (VLBW) infants develop methicillin-resistant Staphylococcus aureus (MRSA) infections, and the morbidity and mortality are similar to that seen i ...

Diseases, Conditions, Syndromes Mar 12, 2012 | not rated yet | 0

Drug helps purge hidden HIV virus, study shows

A team of researchers at the University of North Carolina at Chapel Hill have successfully flushed latent HIV infection from hiding, with a drug used to treat certain types of lymphoma.

HIV & AIDS Mar 08, 2012 | 4.8 / 5 (5) | 0

Blocking telomerase kills cancer cells but provokes resistance, progression

Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...

Cancer Feb 21, 2012 | 5 / 5 (2) | 0 |

Combination of everolimus and exemestane improves survival for women with metastatic breast cancer

In an international Phase III randomized study, everolimus, when combined with the hormonal therapy exemestane, has been shown to dramatically improve progression-free survival, according to research from The University of ...

Cancer Dec 08, 2011 | not rated yet | 0 |

Targeting bacterial gas defenses allow for increased efficacy of numerous antibiotics

Although scientists have known for centuries that many bacteria produce hydrogen sulfide (H2S) it was thought to be simply a toxic by-product of cellular activity. Now, researchers at NYU School of Medicine have discovered ...

Medical research Nov 17, 2011 | not rated yet | 0 |

Connexins: Providing protection to cells destroyed in Type 1 diabetes

Type 1 diabetes is a lifelong disease characterized by high levels of sugar (glucose) in the blood. It is caused by the patient's immune system attacking and destroying the cells in their pancreas that produce the hormone ...

Diseases, Conditions, Syndromes Nov 07, 2011 | not rated yet | 0

Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity

The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes ...

Medical research Sep 29, 2011 | 5 / 5 (2) | 0 |

Newly discovered cell mechanism uses amplified nitric oxide to fight C. diff

Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that ...

Diseases, Conditions, Syndromes Aug 21, 2011 | 5 / 5 (2) | 1 |

New breast cancer model of mutant PI3K recapitulates features of human breast cancer

Scientists from the Friedrich Miescher Institute for Biomedical Research have shown that a mutation in the lipid kinase PI3K, which occurs in about 30% of human breast cancers, itself evokes different forms ...

Cancer Jul 12, 2011 | not rated yet | 0

Copper reduces infection risk by more than 40 percent

Professor Bill Keevil, Head of the Microbiology Group and Director of the Environmental Healthcare Unit at the University of Southampton, has presented research into the mechanism by which copper exerts its ...

Diseases, Conditions, Syndromes Jul 01, 2011 | 5 / 5 (2) | 1 |

Researchers identify genes causing antimalarial drug resistance

Using a pair of powerful genome-search techniques, researchers from the Harvard School of Public Health (HSPH), Harvard University, and the Broad Institute have identified several genes that may be implicated in the malaria ...

Genetics Apr 21, 2011 | not rated yet | 0 |

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