News tagged with resistance mechanisms


The relationship between prenatal stress and obesity is confirmed in rats

The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...

Health created Apr 09, 2013 | popularity 5 / 5 (1) | comments 0

A hijacking of healthy cellular circuits

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...

Cancer created Apr 08, 2013 | popularity not rated yet | comments 0

Cancer cells disguised as stem cells gain extra resistance

Why are certain cancer cells so resistant? The answer may be that they have either retained or acquired attributes normally found in stem cells.

Cancer created Mar 27, 2013 | popularity 5 / 5 (1) | comments 0

New study identifies unique mechanisms of antibiotic resistance

As public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms ...

Diseases, Conditions, Syndromes created Mar 26, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Tiny RNA molecule may have role in polycystic ovary syndrome, insulin resistance

A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers ...

Diabetes created Mar 19, 2013 | popularity 5 / 5 (1) | comments 0

The right dose for oncology

EPFL researchers develop a tool for oncologists using the electrical signature of cancer cells to get just the right treatment dosage for each patient.

Cancer created Mar 04, 2013 | popularity 2 / 5 (2) | comments 0

Medroxyprogesterone acetate linked to immune suppression

(HealthDay)—Use of the injectable contraceptive depot medroxyprogesterone acetate (MPA), common in areas such as sub-Saharan Africa with high HIV-1 prevalence, is associated with suppression of the immune ...

Immunology created Feb 01, 2013 | popularity 5 / 5 (1) | comments 0

To fight incurable metastatic breast cancer, resistance must be broken

One of the most frustrating truths about cancer is that even when a treatment works, it often doesn't work for long because cancer cells find ways to resist. However, researchers reporting studies done in mice in the December ...

Cancer created Dec 10, 2012 | popularity not rated yet | comments 0 | with audio podcast

Understanding of the mechanisms of drug resistance to dual-agent chemotherapy in ovarian cancer

More than half of all patients with ovarian cancer experience recurrent disease and will eventually fail to respond to chemotherapy. The failure of chemotherapy is usually due to the development of resistance to the two main ...

Cancer created Nov 29, 2012 | popularity not rated yet | comments 0

Research may explain why some people with schizophrenia do not respond to treatment

(Medical Xpress)—New research suggests that the molecular mechanism leading to schizophrenia may be different in patients who fail to respond to anti-psychotic medication compared to patients who do respond.

Psychology & Psychiatry created Nov 29, 2012 | popularity not rated yet | comments 0 | with audio podcast

Drug resistance biomarker could improve cancer treatment

Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published ...

Cancer created Nov 21, 2012 | popularity not rated yet | comments 0 | with audio podcast

Research shows diabetes drug improves memory

An FDA-approved drug initially used to treat insulin resistance in diabetics has shown promise as a way to improve cognitive performance in some people with Alzheimer's disease.

Neuroscience created Nov 20, 2012 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Researcher investigate 2-drug synergy to treat drug-resistant chronic myeloid leukemia

(Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together ...

Cancer created Oct 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

The molecular mechanisms behind the benefits of exercise

Leading a sedentary lifestyle increases risk of developing type 2 diabetes. European scientists focused on delineating the mechanisms responsible for the beneficial effects of exercise on our metabolism.

Other created Sep 20, 2012 | popularity not rated yet | comments 0

Researchers find cause of chemotherapy resistance in melanoma

Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0 | with audio podcast