News tagged with resistance mechanisms
Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Cancer
Feb 21, 2012 |
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Culprit behind unchecked angiogenesis identified
German researchers unravel a critical regulatory mechanism controlling blood vessel growth that might help solve drug resistance problems in the future.
Medical research
Mar 29, 2012 |
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Research shows diabetes drug improves memory
An FDA-approved drug initially used to treat insulin resistance in diabetics has shown promise as a way to improve cognitive performance in some people with Alzheimer's disease.
Neuroscience
Nov 20, 2012 |
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Newly discovered cell mechanism uses amplified nitric oxide to fight C. diff
Groundbreaking research encompassing Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, has uncovered a natural defense mechanism that is capable of inactivating the toxin that ...
Diseases, Conditions, Syndromes
Aug 21, 2011 |
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Researchers find cause of chemotherapy resistance in melanoma
Researchers with UC Irvine's Chao Family Comprehensive Cancer Center have identified a major reason why melanoma is largely resistant to chemotherapy.
Cancer
Sep 17, 2012 |
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Cancer cells disguised as stem cells gain extra resistance
Why are certain cancer cells so resistant? The answer may be that they have either retained or acquired attributes normally found in stem cells.
Cancer
Mar 27, 2013 |
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New study identifies unique mechanisms of antibiotic resistance
As public health authorities across the globe grapple with the growing problem of antibiotic resistance, Tufts University School of Medicine microbiologists and colleagues have identified the unique resistance mechanisms ...
Diseases, Conditions, Syndromes
Mar 26, 2013 |
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The right dose for oncology
EPFL researchers develop a tool for oncologists using the electrical signature of cancer cells to get just the right treatment dosage for each patient.
Cancer
Mar 04, 2013 |
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The relationship between prenatal stress and obesity is confirmed in rats
The intrauterine environment plays an important role in the health of the offspring. Now, experts from the University of Navarra affirm that the mother's stress, due to socio-economic or psycho-social causes, is associated ...
Health
Apr 09, 2013 |
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Researcher investigate 2-drug synergy to treat drug-resistant chronic myeloid leukemia
(Medical Xpress)—An interdisciplinary team of researchers has dissected a case of synergy in drug-resistant chronic myeloid leukemia to understand the mechanism by which two drugs, danusertib and bosutinib, work together ...
Cancer
Oct 24, 2012 |
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A hijacking of healthy cellular circuits
Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Cancer
Apr 08, 2013 |
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Research may explain why some people with schizophrenia do not respond to treatment
(Medical Xpress)—New research suggests that the molecular mechanism leading to schizophrenia may be different in patients who fail to respond to anti-psychotic medication compared to patients who do respond.
Psychology & Psychiatry
Nov 29, 2012 |
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Tiny RNA molecule may have role in polycystic ovary syndrome, insulin resistance
A group of tiny RNA molecules with a big role in regulating gene expression also appear to have a role in causing insulin resistance in woman with polycystic ovary syndrome and, perhaps, in all women, researchers ...
Diabetes
Mar 19, 2013 |
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Medroxyprogesterone acetate linked to immune suppression
(HealthDay)—Use of the injectable contraceptive depot medroxyprogesterone acetate (MPA), common in areas such as sub-Saharan Africa with high HIV-1 prevalence, is associated with suppression of the immune ...
Immunology
Feb 01, 2013 |
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Powerful antibody-based strategy suggests a new therapeutic approach to diabetes and obesity
The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes ...
Medical research
Sep 29, 2011 |
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