Could high insulin make you fat? Mouse study says yes
When we eat too much, obesity may develop as a result of chronically high insulin levels, not the other way around. That's according to new evidence in mice reported in the December 4th Cell Metabolism, a Cell ...
Medical research
Dec 04, 2012 |
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American Society of Clinical Oncology issues annual report on state of clinical cancer science
The American Society of Clinical Oncology (ASCO) has just released its annual report on the top cancer advances of the year. Clinical Cancer Advances 2012: ASCO's Annual Report on Progress Against Cancer, highlights major ...
Cancer
Dec 03, 2012 |
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Understanding of the mechanisms of drug resistance to dual-agent chemotherapy in ovarian cancer
More than half of all patients with ovarian cancer experience recurrent disease and will eventually fail to respond to chemotherapy. The failure of chemotherapy is usually due to the development of resistance to the two main ...
Cancer
Nov 29, 2012 |
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Drug resistance biomarker could improve cancer treatment
Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published ...
Cancer
Nov 21, 2012 |
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MicroRNAs can convert normal cells into cancer promoters
Unraveling the mechanism that ovarian cancer cells use to change normal cells around them into cells that promote tumor growth has identified several new targets for treatment of this deadly disease.
Cancer
Nov 21, 2012 |
5 / 5 (2) |
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Metals versus microbes: The biocidal effect of metalloacid-coated surfaces
A new study published in BioMed Central's open access journal Antimicrobial Resistance and Infection Control reports of a phenomenon that could help control the spread of hospital-acquired infections: a surface-coating of met ...
Diseases, Conditions, Syndromes
Nov 13, 2012 |
5 / 5 (1) |
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Key protein interactions involved in neurodegenerative disease revealed
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have defined the molecular structure of an enzyme as it interacts with several proteins involved in outcomes that can influence neurodegenerative ...
Medical research
Nov 08, 2012 |
3.5 / 5 (2) |
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Understanding insulin resistance; Precursor to diabetes can be reversed
Though you may not be living with diabetes, your body could be battling against the hormone insulin. The condition, called insulin resistance, occurs when insulin can't effectively do its job.
Diabetes
Nov 06, 2012 |
5 / 5 (1) |
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Hedgehog pathway key in tamoxifen-resistant breast CA
(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh ...
Cancer
Nov 06, 2012 |
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Recent findings may help to fight melanoma's resistance to chemotherapy
Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...
Cancer
Oct 31, 2012 |
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Neutrons help explain why antibiotics prescribed for chemotherapy cause kidney failure
Neutron scattering experiments have provided new insights into the origin of the side effects of an antifungal drug prescribed all over the world. The analysis conducted by scientists at King's College London ...
Medical research
Oct 29, 2012 |
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A surprise mechanism uncovered in the development of lupus
In a study with a surprising outcome, scientists at Yale School of Medicine have discovered that an enzyme complex known for promoting natural resistance to bacteria and fungi unexpectedly inhibits the development ...
Diseases, Conditions, Syndromes
Oct 25, 2012 |
5 / 5 (2) |
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Scientists target bacterial transfer of resistance genes
The bacterium Streptococcus pneumoniae – which can cause pneumonia, meningitis, bacteremia and sepsis – likes to share its antibiotic-defeating weaponry with its neighbors. Individual cells can pass r ...
Medical research
Oct 24, 2012 |
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Study shows overeating impairs brain insulin function, can lead to diabetes and obesity
New research from Mount Sinai School of Medicine sheds light on how overeating can cause a malfunction in brain insulin signaling, and lead to obesity and diabetes. Christoph Buettner, MD, PhD, Associate Professor of Medicine ...
Overweight and Obesity
Oct 17, 2012 |
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Single gene variant in donors may affect survival of transplanted kidneys
A single genetic variant in kidney donors' cells may help determine whether their transplanted organs will survive long term, according to a study appearing in an upcoming issue of the Journal of the American Society of Ne ...
Other
Oct 11, 2012 |
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