Packaging therapeutic RNAs for targeted treatment of breast cancer
(Medical Xpress) -- Researchers in the Program in Cellular and Molecular Medicine at Boston Children's Hospital and the Immune Disease Institute (PCMM/IDI) have developed a molecular delivery platform that overcomes one of ...
Cancer
Apr 19, 2012 |
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Researchers discover non-surgical test for brain cancer
In a breakthrough for the way brain cancer is diagnosed and monitored, a team of researchers, lead by Anna M. Krichevsky, PhD, of the Center of Neurologic Diseases at Brigham and Women's Hospital (BWH) in Boston and Santosh ...
Cancer
Apr 18, 2012 |
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Promising developments in early diagnosis and treatment of mesothelioma
New results presented at 3rd European Lung Cancer Conference in Geneva, Switzerland show important steps being made to improve the diagnosis and treatment of malignant pleural mesothelioma, an aggressive cancer of the outer ...
Cancer
Apr 18, 2012 |
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Breast cancer study finds new type of mutation
Mayo Clinic researchers have discovered a new class of molecular mutation in various forms of breast cancer, a finding that may shed new light on development and growth of different types of breast tumors. Called fusion ...
Cancer
Apr 16, 2012 |
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New 'genetic bar code' technique establishes ability to derive DNA information from RNA
Researchers from Mount Sinai School of Medicine have developed a method to derive enough DNA information from non-DNA sources—such as RNA—to clearly identify individuals whose biological data are stored in massive ...
Genetics
Apr 08, 2012 |
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Coordinating the circadian clock: Researchers find that molecular pair controls time-keeping and fat metabolism
(PhysOrg.com) -- The 24-hour internal clock controls many aspects of human behavior and physiology, including sleep, blood pressure, and metabolism. Disruption in circadian rhythms leads to increased incidence of many diseases, ...
Genetics
Apr 04, 2012 |
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Compound that halts growth of malaria parasite created
A drug candidate that has shown promise for neutralizing dangerous bacteria also prevents the parasite that causes malaria from growing, new research by a Yale University team headed by Nobel laureate Sidney Altman shows.
Medical research
Apr 02, 2012 |
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PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
Cancer
Apr 01, 2012 |
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Fewer mitochondria in offspring of parents with diabetes
(HealthDay) -- Normal-weight, insulin-resistant individuals whose parents have type 2 diabetes have fewer mitochondria in their muscles due to lower expression of lipoprotein lipase (LPL), according to a study ...
Diabetes
Mar 26, 2012 |
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Double whammy: RNAi enhances lung cancer therapy
Non-small cell lung cancer (NSCLC), the most common form of lung cancer, is usually treated with surgery and chemotherapy. However, a small group of patients can also be helped by treatment with tyrosine kinase inhibitors ...
Cancer
Mar 20, 2012 |
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Disabling cancer cells' defenses against radiation
Researchers at Winship Cancer Institute are developing a technique to remove cancer cells' defenses against radiation.
Cancer
Mar 15, 2012 |
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First-ever integrative 'Omics' profile lets scientist discover, track his diabetes onset
Geneticist Michael Snyder, PhD, has almost no privacy. For more than two years, he and his lab members at the Stanford University School of Medicine pored over his body's most intimate secrets: the sequence of his DNA, the ...
Genetics
Mar 15, 2012 |
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Genome-wide study reveals how key immune sensors arrive at the front lines of infection
In a healthy immune system, invading pathogens trigger a cascade of alerts and responses to fight off the infection. Sensors called toll-like receptors, or TLRs, act as one of the first lines of defense. Two of these sensors, ...
Genetics
Mar 14, 2012 |
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Study shows roles of beta cells and the immune system in Type 1 diabetes
A new JDRF-funded study shows that many of the genes known to play a role in type 1 diabetes (T1D) are expressed in pancreatic beta cells, suggesting that the cell responsible for producing insulin may be playing a part in ...
Diabetes
Mar 09, 2012 |
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New powerful tool measures metabolites in living cells
By engineering cells to express a modified RNA called "Spinach," researchers have imaged small-molecule metabolites in living cells and observed how their levels change over time. Metabolites are the products of individual ...
Medical research
Mar 08, 2012 |
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