Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings. Now, researchers ...
Sep 13, 2019
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A protein known to play a role in cancer may also be increasing fibrosis in scleroderma patients.
Feb 26, 2019
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Scleroderma is a terribly debilitating disease with no effective treatments and the mortality rates are still upwards of 20%-50%, the highest of any rheumatic disease.
Jan 10, 2018
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A discovery by Northwestern Medicine scientists could lead to potential new treatments for breaking the cycle of tissue scarring in people with scleroderma.
Apr 18, 2014
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Johns Hopkins scientists have found evidence that cancer triggers the autoimmune disease scleroderma, which causes thickening and hardening of the skin and widespread organ damage.
Dec 5, 2013
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Using mice, lab-grown cells and clues from a related disorder, Johns Hopkins researchers have greatly increased understanding of the causes of systemic sclerosis, showing that a critical culprit is a defect in the way certain ...
Oct 9, 2013
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Researchers at the University of Pittsburgh School of Medicine have identified an agent that in lab tests protected the skin and lungs from fibrosis, a process that can ultimately end in organ failure and even death because ...
May 30, 2012
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1
A cross-disciplinary University of Alberta research team has uncovered a biological marker for scleroderma that can predict which patients will develop severe disease and could also lead to new treatments.
Jan 9, 2024
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Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology.
Jul 21, 2023
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25
A molecule that was until recently known as a brake on inflammation has now been implicated in fibrosis in scleroderma patients.
Jan 31, 2023
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