Medical research

New technique overcomes genetic cause of infertility

Scientists have created healthy offspring from genetically infertile male mice, offering a potential new approach to tackling a common genetic cause of human infertility.

Genetics

Testosterone concentrations in men affected by genetic makeup

Genetics play an important role in the variation in, and risk of, low testosterone concentrations in men. A study by the CHARGE Sex Hormone Consortium, published in the open-access journal PLoS Genetics on Thursday, 6th October, ...

Neuroscience

Fragile X makes brain cells talk too much, research shows

The most common inherited form of mental retardation and autism, fragile X syndrome, turns some brain cells into chatterboxes, scientists at Washington University School of Medicine in St. Louis report.

Medical research

New insights into infertility-causing sex chromosome disorders

Research carried out by Francis Crick Institute scientists provides new insights into sex chromosome disorders which typically cause infertility, such as Turner syndrome and Klinefelter syndrome. Through their research, the ...

Genetics

For keeping X chromosomes active, chromosome 19 marks the spot

After nearly 40 years of searching, Johns Hopkins researchers report they have identified a part of the human genome that appears to block an RNA responsible for keeping only a single X chromosome active when new female embryos ...

Medical research

Sex hormones skew outcomes in clinical trials—here's how

Clinical research often excludes females from their trials under the assumption that "one size fits all," that a painkiller or antidepressant will be equally effective in subjects of either sex, but a growing number of scientists ...

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