News tagged with signaling pathway
Related topics: protein , cells , cancer cells , genes , breast cancer
Researchers validate the potential of a protein for the treatment of type 2 diabetes
Researchers at the Institute for Research in Biomedicine (IRB Barcelona, Spain)) have discovered that deficiency of a single protein, Mitofusin 2, in muscle and hepatic cells of mice is sufficient to cause ...
Diabetes
Mar 23, 2012 |
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Study reveals new details about a protein that enables cancer cells to start new tumors in distant sites
(Medical Xpress) -- A Loyola University Chicago Stritch School of Medicine study has revealed details of the complex molecular process involving a protein that enables cancer cells to establish tumors in distant parts of ...
Cancer
Mar 14, 2012 |
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New point of attack for breast cancer with poor prognosis
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research describe how the protein phosphatase SHP2 promotes breast cancer with poor prognosis. As they report in the latest ...
Cancer
Mar 05, 2012 |
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Scientists identify crucial cell and signaling pathway in placental blood stem cell niche
(Medical Xpress) -- UCLA stem-cell researchers have identified a certain type of cell and a signaling pathway in the placental niche that play a key role in stopping blood stem cells from differentiating into mature blood ...
Medical research
Mar 01, 2012 |
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Sensitizing tumor cells to radiotherapy
Head and neck squamous cell carcinoma (HNSCC) is the fifth most common cancer worldwide. Tumor resistance to radio- and/or chemotherapy remains a significant clinical problem.
Cancer
Mar 01, 2012 |
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Scientists uncover inflammatory circuit that triggers breast cancer
Although it's widely accepted that inflammation is a critical underlying factor in a range of diseases, including the progression of cancer, little is known about its role when normal cells become tumor cells. Now, scientists ...
Cancer
Feb 23, 2012 |
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Stress pathway identified as potential therapeutic target to prevent vision loss
A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may le ...
Neuroscience
Feb 08, 2012 |
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A thought-provoking new therapeutic target for brain cancer?
Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...
Cancer
Feb 01, 2012 |
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Jak of all trades? Not of leukaemia therapy
About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...
Cancer
Jan 30, 2012 |
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Gatekeeper signal controls skin inflammation
A new study unravels key signals that regulate protective and sometimes pathological inflammation of the skin. The research, published online on January 26th in the journal Immunity by Cell Press, identifies a "gatekeeper" that, ...
Medical research
Jan 26, 2012 |
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Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Cancer
Jan 23, 2012 |
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Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Genetics
Jan 03, 2012 |
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Previously unconnected molecular networks conspire to promote cancer
An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson ...
Cancer
Dec 22, 2011 |
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New discovery could lead to treatment for Angelman syndrome
Results of a new study from the University of North Carolina at Chapel Hill may help pave the way to a treatment for a neurogenetic disorder often misdiagnosed as cerebral palsy or autism.
Genetics
Dec 21, 2011 |
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KS-herpesvirus induces reprogramming of lymphatic endothelial cells to invasive mesenchymal cells
Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma and two other rare lymphoproliferative malignancies, and it is the most common cancer in HIV-infected untreated individuals. Researchers at ...
Cancer
Dec 14, 2011 |
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