Oncology & Cancer

Synthetic RNAs designed to fight cancer

(Medical Xpress)—In search of better cancer treatments, researchers at Washington University School of Medicine in St. Louis have designed synthetic molecules that combine the advantages of two experimental RNA therapies.

Cardiology

New class of drugs lowers cholesterol in first human trial

A single dose of the small interfering ribonucleic acid (siRNA) drug candidate ALN-PCS cut levels of LDL cholesterol (bad cholesterol) in healthy volunteers by up to 57%, and 40% on average more than those given a placebo, ...

Oncology & Cancer

Cholesterol rafts deliver drugs inside cancer cells

DNA, siRNA and miRNA can reprogram cancer cells – that is, if these nucleic acids could cross through the cell membrane. A University of Colorado Cancer Center study published today in the journal Therapeutic Delivery shows ...

Medical research

Naturally occurring protein has a role in chronic pain

Researchers in France and Sweden have discovered how one of the body's own proteins is involved in generating chronic pain in rats. The results, which also suggest therapeutic interventions to alleviate long-lasting pain, ...

Medical research

Emerging pharmaceutical platform may pose risks to retinal health

According to new research by University of Kentucky investigators, an emerging pharmaceutical platform used in treating a variety of diseases may produce unintended and undesirable effects on eye function. The paper, "Short-interfering ...

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