Fibrotic cancers such as gastric cancers are highly resistant to conventional therapies like immune checkpoint inhibitors. Cancer-associated fibroblasts (CAFs) are an important part of the tumor microenvironment contributing ...
Jan 23, 2023
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Research by Oregon State University has uncovered a potential new therapy for pancreatic cancer, whose survival rate is among the lowest of all malignancies.
May 5, 2022
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Researchers have identified a new potential immunotherapy target in pancreatic cancer, which so far has been notoriously resistant to treatment with immune checkpoint blockade drugs effective against a variety of other cancers.
Jan 11, 2019
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Pancreatic cancer has a grim prognosis. It is usually detected after the disease has spread, and chemotherapy tends to do little to slow the cancer's growth. Even with treatment, most patients live only about six months after ...
Oct 26, 2018
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Molecules that are important for a developing fetus have also been shown to drive the spread of ovarian cancer in adult women, according to Sydney researchers.
Jul 18, 2018
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University of North Carolina Lineberger Comprehensive Cancer Center's Jen Jen Yeh, MD, is working to understand the complicated relationship between one of the deadliest cancers and the web of connective tissue that can surround ...
Jan 19, 2018
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Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego have shown that tumors can ensure a more reliable nutrient supply by eliminating the p62 protein in surrounding stromal tissue. Specifically, ...
Oct 6, 2017
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As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal EMBO ...
Mar 2, 2017
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Researchers have moved an important step closer to understanding why pancreatic cancer is so hard to treat. With a median survival of only 6 months and a 5-year survival rate of about 8%, patients tend to be diagnosed when ...
Feb 23, 2017
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Like a stealth jet cloaks itself from radar, cancer cells cloak themselves within tumors by hiding behind a dense layer of cellular material known as stroma.
Feb 24, 2015
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