News tagged with suppressor genes

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...

Apr 15, 2013
popularity 5 / 5 (7) | comments 0 | with audio podcast

Study finds new drug target for metastatic breast cancer

Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...

Apr 11, 2013
popularity 5 / 5 (1) | comments 0

KDM1 may represent a new therapeutic target for glioma

Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...

Apr 08, 2013
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New epigenetic mechanisms for improved cancer therapy

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. ...

Feb 19, 2013
popularity 5 / 5 (3) | comments 0 | with audio podcast

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast