News tagged with t cell activation


Engineered T cells kill tumors but spare normal tissue in an animal model

The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...

Cancer created Apr 07, 2013 | popularity 5 / 5 (7) | comments 0 | with audio podcast

'Rapid response' pathway for immune cell development may improve body's ability to fight recurring infectious threats

Efficient immune protection requires the ability to rapidly recognize intruders that the body has encountered in the past. This is achieved via 'memory' B cells, which develop following immune system activation ...

Medical research created Feb 15, 2013 | popularity 5 / 5 (1) | comments 0

Medroxyprogesterone acetate linked to immune suppression

(HealthDay)—Use of the injectable contraceptive depot medroxyprogesterone acetate (MPA), common in areas such as sub-Saharan Africa with high HIV-1 prevalence, is associated with suppression of the immune ...

Immunology created Feb 01, 2013 | popularity 5 / 5 (1) | comments 0

Study identifies biomarker and potential therapy target in multiple sclerosis

Researchers from Benaroya Research Institute at Virginia Mason (BRI) have found that proteins in the IL-6 signaling pathway may be leveraged as novel biomarkers of multiple sclerosis (MS) to gauge disease activity and as ...

Immunology created Jan 30, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Vaccine trial for Alzheimer's clears key hurdle

A vaccine which revives a promising but long-abandoned path to thwart Alzheimer's disease has cleared a key safety hurdle in human trials, researchers say.

Alzheimer's disease & dementia created Jun 07, 2012 | popularity 5 / 5 (1) | comments 0

Previously unknown cell interaction is key in immune system attacks

Most of the time, the immune system is the body's protector, warding off invading viruses and bacteria before they can lead to infection and disease. But in autoimmune diseases, the immune system does an about face, turning ...

Medical research created Oct 02, 2011 | popularity 5 / 5 (4) | comments 0 | with audio podcast

New insight into immune tolerance furthers understanding of autoimmune disease

It is no easy task to preserve the delicate balance that allows us to maintain a strong immune system that can defend us from harmful pathogens, but that is sensitive enough to correctly identify and spare our own cells. ...

Medical research created Sep 15, 2011 | popularity 5 / 5 (1) | comments 0

Tumor suppressor protein is a key regulator of immune response and balance

St. Jude Children's Research Hospital scientists have identified a key immune system regulator, a protein that serves as a gatekeeper in the white blood cells that produce the "troops" to battle specific infections.

Medical research created Jul 18, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast