Food is essential for life—a daily source of calories and comfort. But for the more than 3 million adults in the United States that suffer from Inflammatory Bowel Disease, or IBD, it is also a daily source of pain and discomfort.
Sep 21, 2021
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Blocking a protein chain reaction makes childhood leukemia cells more sensitive to an existing targeted treatment, a new study shows. The research is still at an early stage, but the drugs used in the study already exist, ...
Feb 25, 2022
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Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism that normally prevent an excessive immune response. Researchers at the ...
Oct 18, 2017
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A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according ...
Apr 15, 2022
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Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, molecules called phosphate groups are constantly ...
Apr 29, 2024
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Researchers at The University of Texas MD Anderson Cancer Center have discovered that a protein called NF-kappa B-inducing kinase (NIK) is essential for the shift in metabolic activity that occurs with T cell activation, ...
Jan 4, 2021
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According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid ...
Aug 18, 2023
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Restoring and improving gut health may be key to slowing HIV progression to AIDS, according to a new study by University of Pittsburgh infectious diseases scientists published today in the journal JCI Insight.
Jul 24, 2023
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Like separate entrance and exit doors on a building, a cell's outer surface has its own doors—channels, pumps, and transporters that selectively control what molecules may enter or exit. In the immune system, T cells—essential ...
Oct 8, 2019
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St. Jude Children's Research Hospital scientists have identified a key immune system regulator, a protein that serves as a gatekeeper in the white blood cells that produce the "troops" to battle specific infections.
Jul 18, 2011
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