Oncology & Cancer

Genotyping errors plague CYP2D6 testing for tamoxifen therapy

Clinical recommendations discouraging the use of CYP2D6 gene testing to guide tamoxifen therapy in breast cancer patients are based on studies with flawed methodology and should be reconsidered, according to the results of ...

Oncology & Cancer

Total darkness at night is key to success of breast cancer therapy

Exposure to light at night, which shuts off nighttime production of the hormone melatonin, renders breast cancer completely resistant to tamoxifen, a widely used breast cancer drug, says a new study by Tulane University School ...

Oncology & Cancer

Gene marker may predict breast cancer response to tamoxifen

(HealthDay)—Researchers have identified genes that may help predict whether a patient with estrogen receptor (ER)-positive breast cancer is likely to benefit from tamoxifen therapy, according to a study published in the ...

Oncology & Cancer

Study confirms long term benefits of tamoxifen

(Medical Xpress)—Taking tamoxifen for 10 rather than five years halves the risk of women dying from the most common kind of breast cancer, according to new research being presented at this year's ASCO conference.

Oncology & Cancer

Mammograms reveal response to common cancer drug

Researchers at Karolinska Institutet have developed a method for assessing the effect of tamoxifen, a common drug to prevent the relapse of breast cancer. The key lies in monitoring changes in the proportion of dense tissue, ...

Oncology & Cancer

25 percent don't complete recommended breast cancer treatment

One-quarter of women who should take hormone-blocking therapies as part of their breast cancer treatment either do not start or do not complete the five-year course, according to a new study led by University of Michigan ...

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