Diseases, Conditions, Syndromes

Tamoxifen ameliorates symptoms of Duchenne muscular dystrophy

A new study has found that tamoxifen, a well-known breast cancer drug, can counteract some pathologic features in a mouse model of Duchenne muscular dystrophy (DMD). At present, no treatment is known to produce long-term ...

Oncology & Cancer

10 years of tamoxifen better than 5, study reports

(HealthDay) —Taking the breast cancer drug tamoxifen for a decade, instead of the standard five years, further reduces the long-term chances of recurrence and risk of dying from the disease, new British research suggests.

Oncology & Cancer

SABCS: Extending tamoxifen to 10 years beneficial in breast CA

(HealthDay)—For women with estrogen receptor (ER)-positive early breast cancer, continuing tamoxifen to 10 years correlates with reduced risk of recurrence and lower breast cancer-specific and overall mortality, according ...

Oncology & Cancer

Hedgehog pathway key in tamoxifen-resistant breast CA

(HealthDay)—Noncanonical Hedgehog (Hh) signaling is activated in tamoxifen-resistant tumors, and the phosphoinositide 3-kinase inhibitor/protein kinase B (PI3K/AKT) pathway plays a key role protecting Hh signaling molecules, ...

Oncology & Cancer

Breast cancer recurrence defined by hormone receptor status

Human epidermal growth factor (HER2) positive breast cancers are often treated with the same therapy regardless of hormone receptor status. New research published in BioMed Central's open access journal Breast Cancer Research ...

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