Anchoring proteins influence glucose metabolism and insulin release
Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases. A-kinase anchoring proteins ...
Medical research
Sep 04, 2012 |
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Researchers prove that leukemias arise from changes that accumulate in blood stem cells
(Medical Xpress)—Imagine that a police bomb squad comes upon a diabolically designed bomb controlled by a tangled mass of different wires, lights and switches, some of which have a real function while others are decoys. ...
Cancer
Aug 30, 2012 |
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Promising new drug target discovered for treatment and prevention of heart failure
A promising new drug target for the treatment and prevention of heart failure has been discovered by researchers at Mount Sinai School of Medicine in New York, NY, US. The study was presented at the ESC Congress 2012 by principal ...
Cardiology
Aug 27, 2012 |
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Precise and persistent cell sabotage: Control of siRNA could aid regenerative medicine, cancer therapy
Some of the body's own genetic material, known as small interfering RNA (siRNA), can be packaged then unleashed as a precise and persistent technology to guide cell behavior, researchers at Case Western Reserve University ...
Medical research
Aug 27, 2012 |
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Therapeutic avenues for Parkinson's investigated at UH
Scientists at the University of Houston (UH) have discovered what may possibly be a key ingredient in the fight against Parkinson's disease.
Parkinson's & Movement disorders
Aug 23, 2012 |
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New nanoparticles that shut off cancer genes shrink tumors in mice
By sequencing cancer-cell genomes, scientists have discovered vast numbers of genes that are mutated, deleted or copied in cancer cells. This treasure trove is a boon for researchers seeking new drug targets, but it is nearly ...
Cancer
Aug 15, 2012 |
5 / 5 (7) |
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New class of proteins allows breast cancer cells to evade tyrosine kinase inhibitors
Aberrant regulation of cell growth pathways is required for normal cells to become cancerous, and in many types of cancer, cell growth is driven by a group of enzymes known as receptor tyrosine kinases (RTKs). The RTK epidermal ...
Cancer
Aug 13, 2012 |
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Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New ...
Cancer
Aug 09, 2012 |
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Scientists use worms to unearth cancer drug targets
Through novel experiments involving small nematode worms, scientists from Wyoming have discovered several genes that may be potential targets for drug development in the ongoing war against cancer. Specifically, researchers ...
Cancer
Aug 09, 2012 |
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Possible muscle disease therapeutic target found
The study of muscular system protein myostatin has been of great interest to researchers as a potential therapeutic target for people with muscular disorders. Although much is known about how myostatin affects muscle growth, ...
Medical research
Aug 06, 2012 |
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New study represents major breakthrough in macular degeneration
University of Kentucky researchers, led by Dr. Jayakrishna Ambati, have made an exciting finding in the "dry" form of age-related macular degeneration known as geographic atrophy (GA). GA is an untreatable condition that ...
Medical research
Aug 06, 2012 |
4.8 / 5 (6) |
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Researchers discover blood biomarker for Lou Gehrig's disease, could lead to new treatments
Researchers from Brigham and Women's Hospital (BWH) are the first to discover that changes in monocytes (a type of white blood cell) are a biomarker for amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. This finding ...
Medical research
Aug 06, 2012 |
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New target for treating diabetes and obesity
Researchers at Washington University School of Medicine in St. Louis have identified a potential target for treating diabetes and obesity.
Medical research
Aug 02, 2012 |
4.8 / 5 (5) |
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IL-10 from donor skin cells helps the body incorporate skin grafts
Scientists have found that the anti-inflammatory molecule, IL-10, may improve success rates of skin autografts (skin moved from one site of the body to another). This information provides a valuable drug target that may benefit ...
Medical research
Jul 31, 2012 |
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Lungs respond to hospital ventilator as if it were an infection
When hospital patients need assistance breathing and are placed on a mechanical ventilator for days at a time, their lungs react to the pressure generated by the ventilator with an out-of-control immune response that can ...
Medical research
Jul 18, 2012 |
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