News tagged with target protein

Specific oxidation regulates cellular functions

For a long time, hydrogen peroxide has been considered as a dangerous metabolite that can damage cells through oxidation. This, however, is not its only role in the cell. Scientists from the German Cancer Research Center ...

Dec 18, 2014
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Toward a better drug against malaria

A research team led by Prof. Dr. Carola Hunte has succeeded in describing how the antimalarial drug atovaquone binds to its target protein. The scientists used x-ray crystallography to determine the three-dimensional ...

Jun 06, 2014
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New molecules doom proteins with kiss of death

Like mobsters following strict orders, newly engineered molecules called "ubiquibodies" can mark specific proteins inside a cell for destruction – a molecular kiss of death that is paving the way for new drug therapies ...

Mar 05, 2014
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New idea for targeting the common cancer protein KRAS

Patients with cancers driven by the protein KRAS, which are particularly hard to treat, may benefit from small molecules that attach to and disrupt the function of a KRAS-containing protein complex, according to results presented ...

Oct 20, 2013
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