Research reveals new drug target urgently needed for tuberculosis therapy
One third of the world is infected with the bacterium that causes tuberculosis (TB), a disease that is increasingly difficult to treat because of wide spread resistance to available drugs. Researchers from the Institute of ...
Diseases, Conditions, Syndromes
Dec 20, 2012 |
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Serendipity points to new potential target and therapy for melanoma
(Medical Xpress)—A University of Colorado Cancer Center study in this month's edition of the Journal of Investigative Dermatology describes a new target and potential treatment for melanoma, the most d ...
Cancer
Dec 20, 2012 |
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Protein kinase Akt identified as arbiter of cancer stem cell fate, paper reports
(Medical Xpress)—The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author ...
Cancer
Dec 20, 2012 |
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Removing protein 'garbage' in nerve cells may help control two neurodegenerative diseases
Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases—amyotrophic lateral sclerosis (ALS), and frontotemporal ...
Medical research
Dec 20, 2012 |
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New research discovery provides therapeutic target for ALS
Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
Genetics
Dec 19, 2012 |
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Harnessing the ID in glioma
Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Cancer
Dec 17, 2012 |
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ASU bioengineer makes key contribution to cancer treatment research
Michael Caplan shares authorship of a paper on cancer treatment research published this week in the prestigious Proceedings of the National Academy of Sciences journal.
Cancer
Dec 17, 2012 |
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Study finds new targets for drugs to defeat aggressive brain tumor
University of Pittsburgh Cancer Institute (UPCI) researchers have identified over 125 genetic components in a chemotherapy-resistant, brain tumor-derived cell line, which could offer new hope for drug treatment to destroy ...
Cancer
Dec 14, 2012 |
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Study reveals alternative pathway through which beta-catenin drives colon cancer
Colon cancer is one of the leading causes of cancer-related death in the United States. Risk factors for the disease are varied and include factors such as advanced age and diet, but most cases share something ...
Cancer
Dec 14, 2012 |
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MicroRNA-218 targets medulloblastoma, most aggressive childhood brain cancer
Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the expression of faulty genes ...
Cancer
Dec 13, 2012 |
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Cancer stem cells isolated from kidney tumors
Scientists have isolated cancer stem cells that lead to the growth of Wilms' tumours, a type of cancer typically found in the kidneys of young children. The researchers have used these cancer stem cells to test a new therapeutic ...
Cancer
Dec 13, 2012 |
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Scientists identify new biomarker for cancer in bone marrow: Promise for patients of multiple myeloma
Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow. Patients with this form of cancer usually do not ...
Cancer
Dec 13, 2012 |
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Study paves way to design drugs aimed at multiple protein targets at once
An international research collaboration led by scientists at the University of North Carolina School of Medicine and the University of Dundee, in the U.K., have developed a way to efficiently and effectively ...
Medical research
Dec 12, 2012 |
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Weekly dose reduces targeted drug's side effects, but not its activity against ALL
A potent chemotherapy agent wrapped within a monoclonal antibody selectively destroys the malignant cells responsible for acute lymphocytic leukemia (ALL) in either weekly or monthly dosing, researchers report at the 54th ...
Cancer
Dec 11, 2012 |
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Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...
Cancer
Dec 10, 2012 |
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