News tagged with targeted therapy


Compound stimulates tumor-fighting protein in cancer therapy

A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team of researchers.

Cancer created Feb 06, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Promising target in treating and preventing the progression of heart failure identified

Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure. The team evaluated failing human and pig hearts and discovered that SUMO1, a so-called "chaperone" ...

Cardiology created Sep 07, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

U-M researchers find new way to clear cholesterol from the blood

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

Cardiology created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Researchers report first success of targeted therapy in most common non-small cell lung cancer

A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone ...

Cancer created Nov 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists identify new target for lung cancer treatment

A team of UC Davis investigators has discovered a protein on the surface of lung cancer cells that could prove to be an important new target for anti-cancer therapy. A series of experiments in mice with lung cancer showed ...

Cancer created Nov 01, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

Cold viruses point the way to new cancer therapies

Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...

Cancer created Oct 16, 2012 | popularity 5 / 5 (5) | comments 0 | with audio podcast

New genetic target found for diuretic therapy

Researchers at the University of Cincinnati (UC) have identified a new genetic target for diuretic therapy in patients with fluid overload—like those with congestive heart failure, liver cirrhosis or kidney failure.

Genetics created Jul 30, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Transforming cancer treatment: Multidrug strategy emerges from new research

A Harvard researcher studying the evolution of drug resistance in cancer says that, in a few decades, “many, many cancers could be manageable.”

Cancer created Jul 11, 2012 | popularity not rated yet | comments 0 | with audio podcast

Energy network within cells may be new target for cancer therapy

Mitochondria, tiny structures within each cell that regulate metabolism and energy use, may be a promising new target for cancer therapy, according to a new study. Manipulation of two biochemical signals that regulate the ...

Cancer created Feb 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Tamoxifen resistance -- and how to defeat it

In the last three decades, thousands of women with breast cancer have taken the drug tamoxifen, only to discover that the therapy doesn't work, either because their tumors do not respond to the treatment at all, or because ...

Cancer created Nov 13, 2011 | popularity not rated yet | comments 0

Researchers map pathway of infection for a common, potentially life-threatening respiratory virus

Researchers at the University of Toronto, The Hospital for Sick Children (SickKids), St. Paul's Hospital and the University of British Columbia have identified a new treatment target for a virus that causes severe lung infections ...

Medical research created Aug 15, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Scientists discover new pathway to potential therapies for advanced prostate cancer

UT Southwestern Medical Center researchers have narrowed the potential drug targets for advanced prostate cancer by demonstrating that late-stage tumors are driven by a different hormonal pathway than was thought previously.

Cancer created Jul 25, 2011 | popularity not rated yet | comments 0 | with audio podcast

Cancer drugs taking shape

In the era of molecular medicine, potentially active compounds for use in cancer therapies can be identified faster than ever before. Yet pinpointing the molecular target of an anticancer compound and deducing ...

Cancer created Apr 22, 2013 | popularity not rated yet | comments 0

Comparing combination therapies for advanced head and neck cancer shows no improvement

Locally advanced squamous cell carcinoma of the head and neck is a potentially curable disease in nearly every patient at the time of diagnosis, yet despite the most aggressive efforts, up to 30-50 percent ...

Cancer created Mar 07, 2013 | popularity 1 / 5 (1) | comments 0